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Merck
CN

Y0000798

Pholcodine for peak identification

European Pharmacopoeia (EP) Reference Standard

别名:

Pholcodine

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关于此项目

经验公式(希尔记法):
C23H30N2O4
化学文摘社编号:
分子量:
398.50
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

pholcodine

制造商/商品名称

EDQM

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal); Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

N6(CCOCC6)CCOc1c2c3c(cc1)C[C@H]4N(CC[C@]53[C@@H](O2)[C@H](C=CC54)O)C

InChI

1S/C23H30N2O4/c1-24-7-6-23-16-3-4-18(26)22(23)29-21-19(5-2-15(20(21)23)14-17(16)24)28-13-10-25-8-11-27-12-9-25/h2-5,16-18,22,26H,6-14H2,1H3/t16?,17-,18+,22+,23+/m1/s1

InChI key

GPFAJKDEDBRFOS-SLITUTQKSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Pholcodine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E Florvaag et al.
Immunology and allergy clinics of North America, 29(3), 419-427 (2009-07-01)
Anaphylactic reactions to neuromuscular blocking agents during general anesthesia constitute a major cause of concern and a great source of debate among anesthesiologists. The authors' recent investigations, taking the striking differences of incidence between Norway and Sweden as the point
E Florvaag et al.
Acta anaesthesiologica Scandinavica, 49(4), 437-444 (2005-03-22)
Anaphylactic reactions to a neuromuscular blocking agent (NMBA) is more than six times as common in Norway as in Sweden, probably due to differences in preoperative sensitization. The prevalence of IgE-sensitization to morphine (MOR) and suxamethonium (SUX) in comparable populations
O M Denk et al.
The Journal of pharmacy and pharmacology, 52(7), 819-829 (2000-08-10)
Three previously unreported manufacturing impurities were isolated from a pholcodine mother liquor using preparative reversed-phase HPLC. The liquor was the residue remaining after recrystallisation of a production batch of pholcodine. The impurities, which are structurally related to pholcodine, were initially
Pholcodine in cough medicines and IgE-sensitization in the EU: an urgent task.
E Florvaag et al.
Allergy, 67(5), 581-582 (2012-03-03)
Paul M Mertes et al.
Current opinion in allergy and clinical immunology, 12(4), 361-368 (2012-07-07)
Immediate hypersensitivity reactions are an important cause for mortality and morbidity in anesthesia. The present review considers reports covering epidemiology, diagnosis, and treatment of these reactions. Immediate hypersensitivity reactions are largely under-reported, adult women being at significantly higher risk than

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