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17884

Sigma-Aldrich

3-(2-Furoyl)quinoline-2-carboxaldehyde

≥95% (HPLC), suitable for fluorescence, BioReagent

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经验公式（希尔记法）:
C15H9NO3
CAS号:
126769-01-5
分子量:
251.24
MDL编号:
MFCD03427748
PubChem化学物质编号:
57647686
NACRES:
NA.32

产品线

BioReagent

检测方案

≥95% (HPLC)

形式

powder

溶解性

methanol: soluble

荧光

λex 486 nm; λem ~600 nm in 0.1 M sodium borate pH 9.0 (after derivatization with glycine)

适用性

suitable for fluorescence

储存温度

2-8°C

SMILES字符串

[H]C(=O)c1nc2ccccc2cc1C(=O)c3ccco3

InChI

1S/C15H9NO3/c17-9-13-11(15(18)14-6-3-7-19-14)8-10-4-1-2-5-12(10)16-13/h1-9H

InChI key

PNCHURHVMDRFTR-UHFFFAOYSA-N

一般描述

3-(2-Furoyl)quinoline-2-carboxaldehyde is a neutral fluorogenic probe for amines for the picomolar assay of proteins by capillary electrophoresis (CE).

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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I H Lee et al.
Analytical chemistry, 70(21), 4546-4548 (1998-11-21)
We report a method for the analysis of picomolar concentration proteins using electrophoretically mediated microanalysis (EMMA) to label proteins on-column with a fluorogenic reagent. Labeling is followed by capillary zone electrophoresis separation and postcolumn detection based on laser-induced fluorescence. The
Alexander V Stoyanov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 780(2), 283-287 (2002-10-29)
Fluorogenic reagents are used for protein labeling when high-sensitivity fluorescence detection is required. Similar to traditional labeling with activated fluorescent dyes, such as fluorescein isothiocyanate, a fluorogenic reaction is expected to change the physical-chemical properties of proteins. Knowledge of these
Tingting Zhao et al.
Electrophoresis, 42(4), 350-359 (2020-11-29)
A quantitative method was developed for the direct identity confirmation and quantification of alendronate using CE-MS combined with a pH-assisted focusing technique, dynamic pH barrage junction focusing. A pH-induced variation in electrophoretic mobility led to online focusing of alendronate at
Cuiru Zhu et al.
Analytical chemistry, 79(2), 765-768 (2007-01-16)
In two-dimensional capillary electrophoresis, a sample undergoes separation in the first dimension capillary by sieving electrophoresis. Fractions are periodically transferred across an interface into a second dimension capillary, where components are further resolved by micellar electrokinetic capillary electrophoresis. Previous instruments
D M Pinto et al.
Electrophoresis, 16(4), 534-540 (1995-04-01)
The fluorescent labeling of peptides at concentrations as low as 10(-8) M can be achieved by using a solid-phase reactor. Using oxidized insulin chain B as a test peptide, we demonstrate the use of an Immobilon CD membrane to capture
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