17884
3-(2-Furoyl)quinoline-2-carboxaldehyde
≥95% (HPLC), suitable for fluorescence, BioReagent
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关于此项目
经验公式（希尔记法）:
C15H9NO3
化学文摘社编号:
分子量:
251.24
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
InChI
1S/C15H9NO3/c17-9-13-11(15(18)14-6-3-7-19-14)8-10-4-1-2-5-12(10)16-13/h1-9H
SMILES string
[H]C(=O)c1nc2ccccc2cc1C(=O)c3ccco3
InChI key
PNCHURHVMDRFTR-UHFFFAOYSA-N
product line
BioReagent
assay
≥95% (HPLC)
form
powder
solubility
methanol: soluble
fluorescence
λex 486 nm; λem ~600 nm in 0.1 M sodium borate pH 9.0 (after derivatization with glycine)
suitability
suitable for fluorescence
storage temp.
2-8°C
Quality Level
General description
3-(2-Furoyl)quinoline-2-carboxaldehyde is a neutral fluorogenic probe for amines for the picomolar assay of proteins by capillary electrophoresis (CE).
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
I H Lee et al.
Analytical chemistry, 70(21), 4546-4548 (1998-11-21)
We report a method for the analysis of picomolar concentration proteins using electrophoretically mediated microanalysis (EMMA) to label proteins on-column with a fluorogenic reagent. Labeling is followed by capillary zone electrophoresis separation and postcolumn detection based on laser-induced fluorescence. The
Melissa M Harwood et al.
Electrophoresis, 28(6), 932-937 (2007-02-20)
The composition of single MCF-7 breast cancer cells is characterized using 2-D CE. Individual MCF-7 cells were aspirated into a 30 mum inner diameter fused-silica capillary and lysed by contact with an SDS-containing buffer. Proteins and other primary amines were
S Hu et al.
Journal of chromatography. A, 924(1-2), 369-375 (2001-08-28)
We report an electrophoretic mobility shift-based method to study the interactions between phospholipids and proteins by capillary electrophoresis with laser-induced fluorescence detection. A fluorogenic dye, 3-(2-furoyl)quinoline-2-carboxaldehyde (FQ), was used to label phosphatidylserine (PS). Then the FQ labeled PS (FQ-PS) was
Tingting Zhao et al.
Electrophoresis, 42(4), 350-359 (2020-11-29)
A quantitative method was developed for the direct identity confirmation and quantification of alendronate using CE-MS combined with a pH-assisted focusing technique, dynamic pH barrage junction focusing. A pH-induced variation in electrophoretic mobility led to online focusing of alendronate at
Alexander V Stoyanov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 780(2), 283-287 (2002-10-29)
Fluorogenic reagents are used for protein labeling when high-sensitivity fluorescence detection is required. Similar to traditional labeling with activated fluorescent dyes, such as fluorescein isothiocyanate, a fluorogenic reaction is expected to change the physical-chemical properties of proteins. Knowledge of these
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