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经验公式(希尔记法):
C10H18O2
化学文摘社编号:
分子量:
170.25
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1721990
产品名称
顺 -2-癸烯酸, ≥95.0% (HPLC)
SMILES string
CCCCCCC\C=C/C(O)=O
InChI key
WXBXVVIUZANZAU-HJWRWDBZSA-N
InChI
1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-
assay
≥95.0% (HPLC)
95.0-105.0% (T)
form
liquid
functional group
carboxylic acid
lipid type
unsaturated FAs
storage temp.
−20°C
Quality Level
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Application
顺-2-癸烯酸可用于研究其对人 HepG2 细胞系的细胞毒性作用。它还用于研究其协同抗螺旋体作用。
Biochem/physiol Actions
顺-2--癸烯酸是一种由铜绿假单胞菌产生的脂肪酸信使(信号分子)。它具有抗生物膜特性并可将大部分细胞转化为浮游(自由游动)表型。顺-2-癸烯酸保留了细菌对抗菌剂的敏感性。它对人体细胞没有任何毒性,因此可用于治疗生物膜相关感染。顺-2--癸烯酸即使在纳摩尔范围内也具有活性。它介导休眠的铜绿假单胞菌和大肠杆菌向其生物活性状态转变,同时不影响细胞数量。顺-2-癸烯酸与抗菌剂一起使用时,对大肠杆菌和肺炎克雷伯菌混菌生物膜有效。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 1
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