19699
顺 -2-癸烯酸
≥95.0% (HPLC)
别名:
2-Decenoic acid, (2Z)-
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关于此项目
经验公式（希尔记法）:
C10H18O2
化学文摘社编号:
分子量:
170.25
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1721990
SMILES string
CCCCCCC\C=C/C(O)=O
InChI key
WXBXVVIUZANZAU-HJWRWDBZSA-N
InChI
1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-
assay
≥95.0% (HPLC), 95.0-105.0% (T)
form
liquid
functional group
carboxylic acid
lipid type
unsaturated FAs
storage temp.
−20°C
Quality Level
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Application
顺-2-癸烯酸可用于研究其对人 HepG2 细胞系的细胞毒性作用。它还用于研究其协同抗螺旋体作用。
Biochem/physiol Actions
顺-2--癸烯酸是一种由铜绿假单胞菌产生的脂肪酸信使（信号分子）。它具有抗生物膜特性并可将大部分细胞转化为浮游（自由游动）表型。顺-2-癸烯酸保留了细菌对抗菌剂的敏感性。它对人体细胞没有任何毒性，因此可用于治疗生物膜相关感染。顺-2--癸烯酸即使在纳摩尔范围内也具有活性。它介导休眠的铜绿假单胞菌和大肠杆菌向其生物活性状态转变，同时不影响细胞数量。顺-2-癸烯酸与抗菌剂一起使用时，对大肠杆菌和肺炎克雷伯菌混菌生物膜有效。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 1
Azadeh Rahmani-Badi et al.
Archives of oral biology, 60(11), 1655-1661 (2015-09-10)
To investigate the ability of cis-2-decenoic acid (C2DA) to induce dispersion in single-species biofilms formed by Streptococcus mutans and Candida albicans, as well as to remove their bacterial-fungal dual-species biofilms when combined with low concentrations of chlorhexidine (CHX). For biofilm
Majed Alrobaian et al.
Molecules (Basel, Switzerland), 24(10) (2019-05-28)
Two series of novel 5-arylazo-3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galacto pyranosyloxy) pyridines and 3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galactopyranosyloxy) pyridines were synthesized in high yields utilizing a microwave-assisted synthesis tool guided by the principles of green chemistry. The chemical structures of the new substances were confirmed on the basis of
Han-Shin Kim et al.
Biotechnology and bioengineering, 118(1), 82-93 (2020-09-04)
Bacterial biofilm formation causes serious problems in various fields of medical, clinical, and industrial settings. Antibiotics and biocide treatments are typical methods used to remove bacterial biofilms, but biofilms are difficult to remove effectively from surfaces due to their increased
A Goc et al.
Journal of applied microbiology, 123(3), 637-650 (2017-06-24)
Borrelia sp., a causative pathogenic factor of Lyme disease (LD), has become a major public health threat. Current treatments based on antibiotics often lead to relapse after their withdrawal. Naturally derived substances that could work synergistically to display higher efficacy
Martha María Juárez-Rodríguez et al.
Frontiers in cellular and infection microbiology, 10, 597517-597517 (2021-02-16)
Blocking virulence is a promising alternative to counteract Pseudomonas aeruginosa infections. In this regard, the phenomenon of cell-cell communication by quorum sensing (QS) is an important anti-virulence target. In this field, fatty acids (FA) have gained notoriety for their role
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