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Merck
CN

19699

-2-癸烯酸

≥95.0% (HPLC)

别名:

2-Decenoic acid, (2Z)-

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关于此项目

经验公式(希尔记法):
C10H18O2
化学文摘社编号:
分子量:
170.25
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1721990
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产品名称

-2-癸烯酸, ≥95.0% (HPLC)

SMILES string

CCCCCCC\C=C/C(O)=O

InChI key

WXBXVVIUZANZAU-HJWRWDBZSA-N

InChI

1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-

assay

≥95.0% (HPLC)
95.0-105.0% (T)

form

liquid

functional group

carboxylic acid

lipid type

unsaturated FAs

storage temp.

−20°C

Quality Level

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Application

-2-癸烯酸可用于研究其对人 HepG2 细胞系的细胞毒性作用。它还用于研究其协同抗螺旋体作用。

Biochem/physiol Actions

-2--癸烯酸是一种由铜绿假单胞菌产生的脂肪酸信使(信号分子)。它具有抗生物膜特性并可将大部分细胞转化为浮游(自由游动)表型。-2-癸烯酸保留了细菌对抗菌剂的敏感性。它对人体细胞没有任何毒性,因此可用于治疗生物膜相关感染。-2--癸烯酸即使在纳摩尔范围内也具有活性。它介导休眠的铜绿假单胞菌大肠杆菌向其生物活性状态转变,同时不影响细胞数量。-2-癸烯酸与抗菌剂一起使用时,对大肠杆菌和肺炎克雷伯菌混菌生物膜有效。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Majed Alrobaian et al.
Molecules (Basel, Switzerland), 24(10) (2019-05-28)
Two series of novel 5-arylazo-3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galacto pyranosyloxy) pyridines and 3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galactopyranosyloxy) pyridines were synthesized in high yields utilizing a microwave-assisted synthesis tool guided by the principles of green chemistry. The chemical structures of the new substances were confirmed on the basis of
Thomas Tørring et al.
Chembiochem : a European journal of chemical biology, 18(7), 638-646 (2017-01-25)
Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative gammaproteobacterial pathogen that infects and intracellularly replicates in human macrophages and a variety of protozoa. L. pneumophila encodes an orphan biosynthetic gene cluster (BGC) that contains isocyanide-associated biosynthetic genes and
Azadeh Rahmani-Badi et al.
Archives of oral biology, 60(11), 1655-1661 (2015-09-10)
To investigate the ability of cis-2-decenoic acid (C2DA) to induce dispersion in single-species biofilms formed by Streptococcus mutans and Candida albicans, as well as to remove their bacterial-fungal dual-species biofilms when combined with low concentrations of chlorhexidine (CHX). For biofilm
A Goc et al.
Journal of applied microbiology, 119(6), 1561-1572 (2015-10-13)
Little is known about the effects of phytochemicals against Borrelia sp. causing Lyme disease. Current therapeutic approach to this disease is limited to antibiotics. This study examined the anti-borreliae efficacy of several plant-derived compounds and micronutrients. We tested the efficacy
Martha María Juárez-Rodríguez et al.
Frontiers in cellular and infection microbiology, 10, 597517-597517 (2021-02-16)
Blocking virulence is a promising alternative to counteract Pseudomonas aeruginosa infections. In this regard, the phenomenon of cell-cell communication by quorum sensing (QS) is an important anti-virulence target. In this field, fatty acids (FA) have gained notoriety for their role

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