30020
D-环丝氨酸
别名:
(R)-4-氨基-3-异噁唑烷酮, 4-氨基-3-异噁唑烷酮
生物来源
synthetic
质量水平
表单
powder
效能
≥900 μg per mg
颜色
white to off-white
mp
147 °C (dec.) (lit.)
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
作用机制
cell wall synthesis | interferes
储存温度
−20°C
SMILES字符串
N[C@@H]1CONC1=O
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChI key
DYDCUQKUCUHJBH-UWTATZPHSA-N
正在寻找类似产品? 访问 产品对比指南
一般描述
Chemical structure: amino acid derivatives
应用
D-Cycloserine acts as inhibitor of various enzymes.
生化/生理作用
作用方式：抑制细胞壁生物合成（D-Ala 肽键形成）。同时可防止将D-Ala转化为L-Ala。抑菌性。
作用于 NMDA 谷氨酸能受体的甘氨酸调节位点的部分激动剂；抗革兰氏阴性细菌的抗生素。
干预方式：D-Ala转运干预。
作用于 NMDA 谷氨酸能受体的甘氨酸调节位点的部分激动剂；抗革兰氏阴性细菌的抗生素。
干预方式：D-Ala转运干预。
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
包装
1g, 5g, 25g
其他说明
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Air sensitive. Keep in a dry place.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Michael L Sulkowski et al.
Current psychiatry reviews, 10(4), 317-324 (2014-11-11)
Variants of exposure therapy are effective for treating obsessive-compulsive and related disorders (OCRDs). However, significant numbers of patients do not respond adequately to exposure therapy resulting in continued distress and functional impairment. Therefore, novel approaches to augmenting exposure therapy are
M.K. Jain
Handbook of Enzyme Inhibitors, 112-112 (1982)
Mary M Torregrossa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(31), 10526-10533 (2010-08-06)
Extinction therapy has been proposed as a method to reduce the motivational impact of drug-associated cues to prevent relapse. Cue extinction therapy, however, takes place in a novel context (e.g., treatment facility), and is unlikely to be effective due to
Rami Yaka et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(9), 2033-2041 (2007-03-14)
Traumatic brain injury triggers a massive glutamate efflux, activation of NMDA receptor channels, and cell death. Recently, we reported that NMDA receptors in mice are down-regulated from hours to days following closed head injury (CHI), and treatment with NMDA improved
Stefan G Hofmann et al.
Current psychiatry reports, 17(1), 532-532 (2014-11-22)
Although cognitive behavioral therapy (CBT) is a generally effective treatment for treating anxiety disorders, there is clearly still room for further improvements. Recent advances in neuroscience of extinction learning led to novel clinical strategies to augment exposure-based treatments with d-cycloserine
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持