30432
丹酰尸胺
BioReagent, suitable for fluorescence, ≥99.0% (HPLC)
别名:
N-（5-氨基戊基）-5-二甲基氨基萘-1-磺酰胺, N-（二甲基氨基萘磺酰）-1，5-戊二胺, 丹酰尸胺
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C17H25N3O2S
化学文摘社编号:
分子量:
335.46
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
EC Number:
233-326-9
Beilstein/REAXYS Number:
2951070
MDL number:
产品名称
丹酰尸胺, BioReagent, suitable for fluorescence, ≥99.0% (HPLC)
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN
InChI key
MLEBFEHOJICQQS-UHFFFAOYSA-N
InChI
1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3
product line
BioReagent
assay
≥99.0% (HPLC)
mp
137-140 °C
fluorescence
λex 335 nm; λem 518 nm in methanol
λex 338 nm; λem 500 nm (Reaction product)
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
丹酰戊二胺（MDC），一种自荧光染料，被用来监测细胞自我吞噬。 因为离子捕获和特异性膜脂互作，MDC在自噬泡中累积。
Biochem/physiol Actions
纤维蛋白稳定因子抑制剂；表皮生长因子（EGF）内化抑制剂酰胺顺反异构转化酶分析荧光底物。
自发荧光染料丹酰尸胺或单丹磺酰尸胺（MDC）通常用于监测自噬。 由于离子捕获和与膜脂质的特异性相互作用的组合，单丹磺酰尸胺优先在自噬泡中积累。
Other Notes
在甲醇（10 mg/mL）中测试丹酰尸胺的溶解度。据报道，丹酰尸胺可溶于 DMSO 和乙酸。
Packaging
无底玻璃瓶。内容物在插入式融锥内。
空气敏感，在惰性气体下处理
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Qi Jiang et al.
The Journal of urology, 188(4), 1361-1368 (2012-08-22)
Androgen receptor has a critical role in prostate cancer development and progression. Cell death via autophagy may also contribute to prostate cancer progression. We determined the role and regulatory effects of androgen receptor on the autophagy process of prostate cancer
Fibrin-stabilizing factor inhibitors. 3. Sulphonamides related to monodansylcadaverine.
J L Nilsson et al.
Acta pharmaceutica Suecica, 8(5), 497-504 (1971-11-01)
H T Haigler et al.
The Journal of biological chemistry, 255(4), 1239-1241 (1980-02-25)
The binding and internalization of 125I-epidermal growth factor (125I-EGF) was studied in cultures of BALB 3T3 cells using a novel method that involved removal of cell-surface hormone by treatment with acetic acid under conditions that did not remove internalized hormone.
Transamidating enzymes. I. Rapid chromatographic assays.
L Lorand et al.
Analytical biochemistry, 44(1), 207-220 (1971-11-01)
S N Murthy et al.
The Journal of biological chemistry, 269(36), 22907-22911 (1994-09-09)
Elevating the intracellular concentration of Ca2+ ions in human erythrocytes leads to the formation of membrane-associated polymers, composed of skeletal and cytoplasmic proteins. The anion transporter band 3 serves as a membrane anchor for this N epsilon-(gamma-glutamyl)lysine cross-linked polymer. The
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持