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Merck
CN

30432

Sigma-Aldrich

丹酰尸胺

BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

别名:

N-(5-氨基戊基)-5-二甲基氨基萘-1-磺酰胺, N-(二甲基氨基萘磺酰)-1,5-戊二胺, 丹酰尸胺

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500 μG
CN¥4,729.52

CN¥4,729.52


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500 μG
CN¥4,729.52

About This Item

经验公式(希尔记法):
C17H25N3O2S
CAS Number:
分子量:
335.46
Beilstein:
2951070
EC 号:
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32

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产品线

BioReagent

质量水平

方案

≥99.0% (HPLC)

mp

137-140 °C

荧光

λex 335 nm; λem 518 nm in methanol
λex 338 nm; λem 500 nm (Reaction product)

适用性

suitable for fluorescence

储存温度

−20°C

SMILES字符串

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN

InChI

1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

InChI key

MLEBFEHOJICQQS-UHFFFAOYSA-N

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SAB4200182T7915T9698
Gene Information

human ... GSR(2936)

Gene Information

human ... GSR(2936)

Gene Information

Escherichia coli K12 ... trxB(949054)

Gene Information

rat ... Txnrd1(58819)

specific activity

≥10 units/mg protein

specific activity

-

specific activity

>25 units/mg protein (Bradford)

specific activity

≥100 units/mg protein (Bradford)

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

-

form

buffered aqueous solution

form

buffered aqueous solution

form

ammonium sulfate suspension

form

buffered aqueous glycerol solution

UniProt accession no.

P00390

UniProt accession no.

P00390

UniProt accession no.

P0A9P4

UniProt accession no.

O89049

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

应用

丹酰戊二胺(MDC),一种自荧光染料,被用来监测细胞自我吞噬。 因为离子捕获和特异性膜脂互作,MDC在自噬泡中累积。

生化/生理作用

纤维蛋白稳定因子抑制剂;[1]表皮生长因子(EGF)内化抑制剂[2]酰胺顺反异构转化酶分析荧光底物。[3][4]
自发荧光染料丹酰尸胺或单丹磺酰尸胺(MDC)通常用于监测自噬。 由于离子捕获和与膜脂质的特异性相互作用的组合,单丹磺酰尸胺优先在自噬泡中积累。

包装

无底玻璃瓶。内容物在插入式融锥内。
空气敏感,在惰性气体下处理

其他说明

在甲醇(10 mg/mL)中测试丹酰尸胺的溶解度。据报道,丹酰尸胺可溶于 DMSO 和乙酸。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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