生物来源
rabbit
偶联物
unconjugated
抗体形式
Ig fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (338A-74)
vial of 0.5 mL concentrate (338A-75)
bottle of 1.0 mL predilute (338A-77)
vial of 1.0 mL concentrate (338A-76)
bottle of 7.0 mL predilute (338A-78)
制造商/商品名称
Cell Marque®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
控制
thymus
运输
wet ice
储存温度
2-8°C
可视化
nuclear
基因信息
human ... DNTT(1791)
一般描述
TdT (terminal deoxynucleotidyl transferase) is a template-independent DNA polymerasethat adds nucleotides randomly to single-stranded DNA. This randomization plays a role inacquired immunity by increasing antigen receptor diversity and aiding in the generation ofimmunoglobulins and T-cell antigen receptors. TdT immunoreactivity is observed mainly in the thymus. Anti-TdT is often used to visualize lymphoblastic lymphomas and has also beenobserved in some cases of acute myeloid leukemia.
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
分析说明
 IVD |  IVD |  IVD |  RUO |
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
TdT Positive Control Slides, Product No. 338S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
法律信息
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
A Practical Approach to Diagnosis, 312-316 (1990)
A Orazi et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 7(5), 582-586 (1994-06-01)
Terminal deoxynucleotidyl transferase (TdT) represents a useful marker for the diagnosis of acute lymphoblastic leukemia and lymphoblastic lymphoma. It is usually assayed in fresh tissue or cell suspensions by enzyme analysis, immunofluorescence, or immunoperoxidase. We have obtained satisfactory staining for
R A Soslow et al.
Human pathology, 28(10), 1158-1165 (1997-10-29)
We propose that 12E7 (CD99) expression, along with TdT, bcl-2, and CD34 reactivity in lymphoblastic lymphoma (LyL)/acute lymphoblastic leukemia (ALL), distinguishes this group of neoplasms from small noncleaved cell lymphomas (SNCLs) in both pediatric and adult patients, thereby narrowing the
Ewing sarcoma vs lymphoblastic leukemia.
S Hirschl
American journal of clinical pathology, 115(6), 933-934 (2001-06-08)
M Ozdemirli et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(11), 1175-1182 (2001-11-14)
We encountered a child with an intraosseous small round cell tumor that was negative for LCA, CD20 (L26), and CD3 and positive for vimentin, CD99 (MIC-2), and periodic acid-Schiff. The tumor exhibited rosette-like formations. This case was initially interpreted as
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