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Merck
CN

37150

Sigma-Aldrich

3,3′-Diheptylthiacarbocyanine iodide

别名:

DiSC7(3)

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关于此项目

经验公式(希尔记法):
C31H41IN2S2
化学文摘社编号:
分子量:
632.71
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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表单

solid

荧光

λex 562 nm; λem 575 nm in methanol

适用性

in accordance for fluorescence
suitable for fluorescence

SMILES字符串

[I-].CCCCCCCN1C(\Sc2ccccc12)=C/C=C/c3sc4ccccc4[n+]3CCCCCCC

InChI

1S/C31H41N2S2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31;/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3;1H/q+1;/p-1

InChI key

QJIIDBGAPSEKOV-UHFFFAOYSA-M

应用

3,3′-Diheptylthiacarbocyanine iodide [DiSC7(3)], a cyanine dye, may be used similar to 3,3′-dipropylthiadicarbocyanine iodide [DiSC(3)(5)] for membrane potential studies.

其他说明

Cyanine dye for measuring membrane potential

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles.
P J Sims et al.
Biochemistry, 13(16), 3315-3330 (1974-07-30)
Jaromír Plášek et al.
Journal of bioenergetics and biomembranes, 44(5), 559-569 (2012-07-20)
The fluorescent dye 3,3'-dipropylthiadicarbocyanine, diS-C(3)(3), is a suitable probe to monitor real changes of plasma membrane potential in yeast cells which are too small for direct membrane potential measurements with microelectrodes. A method presented in this paper makes it possible
R J W Brooijmans et al.
Journal of bacteriology, 189(14), 5203-5209 (2007-05-15)
Lactococcus lactis, a facultative anaerobic lactic acid bacterium, is known to have an increased growth yield when grown aerobically in the presence of heme. We have now established the presence of a functional, proton motive force-generating electron transfer chain (ETC)
Adam D Pfefferle et al.
Disease models & mechanisms, 12(7) (2019-06-20)
The Wnt gene family encodes an evolutionarily conserved group of proteins that regulate cell growth, differentiation and stem cell self-renewal. Aberrant Wnt signaling in human breast tumors has been proposed as a driver of tumorigenesis, especially in the basal-like tumor
Jaeyong Cho et al.
Biochimica et biophysica acta, 1828(3), 1153-1158 (2012-12-25)
Dioscin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica. We investigated the antifungal effect of dioscin against different fungal strains and its antifungal mechanism(s) in Candida albicans cells. Using the propidium iodide

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