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Merck
CN

390M-1

Sigma-Aldrich

GATA3 (L50-823) Mouse Monoclonal Antibody

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41

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生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

L50-823, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (390M-14)
vial of 0.5 mL concentrate (390M-15)
bottle of 1.0 mL predilute (390M-17)
vial of 1.0 mL concentrate (390M-16)
bottle of 7.0 mL predilute (390M-18)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1κ

控制

breast carcinoma, urothelial carcinoma

运输

wet ice

储存温度

2-8°C

可视化

nuclear

基因信息

human ... GATA3(2625)

相关类别

一般描述

GATA binding protein 3 or GATA3, is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. The human GATA3 gene has been mapped to chromosome10p15. GATA3 expression is primarily seen in breast carcinoma and urothelial carcinoma. Anti-GATA3 can also be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

分析说明


IVD
IVD
IVD
RUO

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
GATA3 Positive Control Slides, Product No. 390S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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分析证书(COA)

Lot/Batch Number
0000459006
0000459006
0000459002
0000459002
0000456214

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M C Labastie et al.
Genomics, 21(1), 1-6 (1994-05-01)
GATA3, a member of the GATA family that is abundantly expressed in the T-lymphocyte lineage, is thought to participate in T-cell receptor gene activation through binding to enhancers. To understand GATA3 gene regulation, we cloned the human gene and the
V Joulin et al.
The EMBO journal, 10(7), 1809-1816 (1991-07-01)
The human GATA1, hGATA1 (previously called NF-E1, GF-1 or Eryf-1), a major sequence-specific DNA-binding protein of the erythrocytic lineage, is a member of a zinc-finger family of DNA-binding proteins. We report here the cloning of a human cDNA for a
Haiyan Liu et al.
American journal of clinical pathology, 138(1), 57-64 (2012-06-19)
GATA3 expression has been reported in urothelial and breast carcinomas; however, the published data on GATA3 expression in tumors from other organs are limited. Immunohistochemical evaluation of GATA3 expression in 1,110 carcinomas and 310 cases of normal tissue using tissue
John P T Higgins et al.
The American journal of surgical pathology, 31(5), 673-680 (2007-04-27)
The morphologic distinction between prostate and urothelial carcinoma can be difficult. To identify novel diagnostic markers that may aid in the differential diagnosis of prostate versus urothelial carcinoma, we analyzed expression patterns in prostate and bladder cancer tissues using complementary
Huadong Lai et al.
International journal of cancer, 149(12), 2099-2115 (2021-09-05)
Bladder cancer represents a highly heterogeneous disease characterized by distinct histological, molecular and clinical phenotypes, and a detailed analysis of tumor cell invasion and crosstalks within bladder tumor cells has not been determined. Here, we applied droplet-based single-cell RNA sequencing

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Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

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