44977
DISBAC2(3), Voltage Sensitive Probe
≥98% (HPLC)
别名:
5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol
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关于此项目
经验公式（希尔记法）:
C19H24N4O4S2
CAS Number:
分子量:
436.55
Beilstein:
1232950
EC 号:
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
质量水平
方案
≥98% (HPLC)
荧光
λex 535 nm; λem 560 nm in DMSO
适用性
complies for Infrared spectrum
储存温度
−20°C
SMILES字符串
CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S
InChI
1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+
InChI key
VJYNRXFXHKIGLT-MDZDMXLPSA-N
应用
DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Konstantinos Papadimitriou et al.
International journal of food microbiology, 111(3), 197-205 (2006-08-29)
Flow cytometry in combination with fluorescence probes was applied to rapidly assess the physiological status of Streptococcus macedonicus ACA-DC 198, a newly described member of the lactic acid bacteria group with technologically important features (e.g. lantibiotic production). A sonication procedure
P He et al.
Microvascular research, 50(2), 183-198 (1995-09-01)
The membrane potential is an important modulator of calcium ion flux into endothelial cells of venular microvessels. We developed a method to measure the membrane potential of endothelial cells forming the walls of individually perfused microvessels under the same experimental
A G Cabado et al.
Journal of cellular physiology, 158(2), 309-316 (1994-02-01)
We studied, in different ionic conditions, the effect of various agents on the membrane potential of rat peritoneal mast cells using the fluorescent probe bisoxonol. Ouabain and ionophore A23187 lead to a fast depolarization of the plasma membrane of mast
Yi Tang et al.
Assay and drug development technologies, 4(4), 461-471 (2006-09-02)
Adenosine-3',5'-cyclic monophosphate (cAMP) conveys the signals from G-protein coupled receptors (GPCRs) and regulates a variety of downstream cellular events. However, there are few robust assays available for measuring cAMP in live cells. Most of the existing cAMP assays require cell
M Renier et al.
Human gene therapy, 6(10), 1275-1283 (1995-10-01)
Cystic fibrosis is caused by defects in a chloride-transporting protein termed cystic fibrosis transmembrane conductance regulator (CFTR). This study presents an innovative procedure to evaluate expression of functional CFTR. The technique uses the potential-sensitive probe bis-(1,3-diethylthiobarbituric acid) trimethine oxonol or
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