51063
Obidoxime chloride
≥95.0% (HPLC)
别名:
1,1′-(Oxydimethylene)bis(pyridinium-4-carbaldoxime) dichloride, Bis(4-formylpyridiniomethyl) ether dioxime, Toxogonin
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H16Cl2N4O3
化学文摘社编号:
分子量:
359.21
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
204-059-5
Beilstein/REAXYS Number:
4117377
MDL number:
产品名称
Obidoxime chloride, ≥95.0% (HPLC)
InChI key
ZIFJVJZWVSPZLE-UHFFFAOYSA-N
InChI
1S/C14H14N4O3.2ClH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H
SMILES string
[Cl-].[Cl-].O\N=C\c1cc[n+](COC[n+]2ccc(cc2)\C=N\O)cc1
assay
≥95.0% (HPLC)
form
powder or crystals
Quality Level
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
Antidote for organophosphate nerve agent poisoning
Antidote for organophosphate nerve agent poisoning, but, as with other oxime agents, not full spectrum. Obidoxime fails primarily to reactivate acetylcholinesterase that has been inhibited with cyclosarin.
General description
active agent in Toxogonin
Legal Information
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Franz Worek et al.
Toxicology letters, 200(1-2), 19-23 (2010-10-26)
Previous in vitro studies showed marked species differences in the reactivating efficiency of oximes between human and animal acetylcholinesterase (AChE) inhibited by organophosphorus (OP) nerve agents. These findings provoked the present in vitro study which was designed to determine the
Jürgen Kufleitner et al.
Journal of microencapsulation, 27(7), 594-601 (2010-10-07)
Intoxication with organophosphorous nerve agents such as paraoxon requires immediate administration of antidotes such as oximes. However, the oximes lack sufficient activity in the central nervous system as they are unable to rapidly penetrate the blood-brain barrier (BBB) in therapeutically
Yossi Rosman et al.
Journal of applied toxicology : JAT, 32(6), 409-416 (2011-08-24)
Organophosphate intoxication induces neural toxicity as demonstrated in histological analysis of poisoned animals. Diffusion-weighted magnetic resonance imaging (DWMRI) enables early noninvasive characterization of biological tissues based on their water diffusion characteristics. Our objectives were to study the application of MRI
Marloes J A Joosen et al.
Chemico-biological interactions, 188(1), 255-263 (2010-07-06)
The nerve agent VX is most likely to enter the body via liquid contamination of the skin. After percutaneous exposure, the slow uptake into the blood, and its slow elimination result in toxic levels in plasma for a period of
R M Dawson
Journal of applied toxicology : JAT, 14(5), 317-331 (1994-09-01)
A review was conducted of papers describing the use of N-methyl-2-pyridinealdoxime (PAM), toxogonin or HI-6 as antidotes to the nerve agents tabun, sarin, soman and VX. The review included use of the oxime alone, oxime plus atropine and oxime plus
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持