描述
For research or for further manufacturing use.
质量水平
无菌性
sterile-filtered
表单
liquid
储存条件
protect from light
技术
cell culture | mammalian: suitable
组分
L-glutamine: no
运输
ambient
储存温度
2-8°C
应用
Claycomb培养基是以建立HL-1细胞系的William Claycomb博士命名的，它专用于培养小鼠心肌细胞生长。HL-1是第一个能够在 体外维持分化心肌细胞表型和收缩活性的细胞系。HL-1细胞系可用于研究心肌梗塞后的心肌细胞肥大、测试新型心脏治疗药物和疗法、生产高水平心肌蛋白以及研究成熟心肌细胞特异性基因。补充100 μM去甲肾上腺素、10％胎牛血清（FBS）和4mM L-谷氨酰胺的Claycomb培养基，将能够维持HL-1细胞系和成熟心肌细胞的行为。在光学显微镜下观察HL-1细胞时，可以观察到细胞个体和群体的收缩随心肌细胞逐渐融合而变得更加频繁。
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
动植物来源培养基
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Malou van den Boogaard et al.
Cell reports, 28(10), 2704-2714 (2019-09-05)
The human ether-a-go-go-related gene KCNH2 encodes the voltage-gated potassium channel underlying IKr, a current critical for the repolarization phase of the cardiac action potential. Mutations in KCNH2 that cause a reduction of the repolarizing current can result in cardiac arrhythmias
L A Sikkink et al.
Cell death & disease, 1, e98-e98 (2010-01-01)
Light-chain amyloidosis (AL) is a devastating protein-misfolding disease characterized by abnormal proliferation of plasma cells in the bone marrow that secrete monoclonal immunoglobulin light chains that misfold and form amyloid fibrils, thus causing organ failure and death. Numerous reports on
Jan Hendrik van Weerd et al.
eLife, 9 (2020-07-17)
Genome-wide association studies have implicated common genomic variants in the gene desert upstream of TBX3 in cardiac conduction velocity. Whether these noncoding variants affect expression of TBX3 or neighboring genes and how they affect cardiac conduction is not understood. Here
Hongwei Wu et al.
Biochemical and biophysical research communications, 471(1), 240-246 (2016-01-26)
Mounting studies have illustrated an important role of HOTAIR in cancer progress, but few studies have reported its function in cardiac disease, including cardiac-associated sepsis. This study aimed to investigate the function of HOTAIR in sepsis, involving its association with
Amanah Abraham et al.
The Journal of biological chemistry, 293(52), 19974-19981 (2018-11-23)
Human babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the genus Babesia Clinical cases caused by Babesia duncani have been associated with high parasite burden, severe pathology, and death. In both mice and hamsters, the parasite causes
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