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Merck
CN

52649

Sigma-Aldrich

六亚甲基二异氰酸酯

puriss., ≥99.0% (GC)

别名:

1,6-己二异氰酸酯

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关于此项目

线性分子式:
OCN(CH2)6NCO
CAS Number:
分子量:
168.19
Beilstein:
956709
EC 号:
MDL编号:
UNSPSC代码:
12352118
PubChem化学物质编号:
NACRES:
NA.25
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等级

puriss.

质量水平

方案

≥99.0% (GC)

折射率

n20/D 1.453

沸点

82-85 °C/0.1 mmHg

密度

1.047 g/mL at 20 °C (lit.)
1.047 g/mL at 20 °C

SMILES字符串

O=C=NCCCCCCN=C=O

InChI

1S/C8H12N2O2/c11-7-9-5-3-1-2-4-6-10-8-12/h1-6H2

InChI key

RRAMGCGOFNQTLD-UHFFFAOYSA-N

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应用

双功能试剂

警示用语:

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

闪点(°F)

266.0 °F - Pensky-Martens closed cup

闪点(°C)

130 °C - Pensky-Martens closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

非剧毒-急性毒性1
危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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G Bieler et al.
Occupational medicine (Oxford, England), 61(6), 440-442 (2011-08-10)
Occupational diisocyanate-induced extrinsic allergic alveolitis (EAA) is a rare and probably underestimated diagnosis. Two acute occupational EAA cases have been described in this context, but neither of them concerned hexamethylene diisocyanate (HDI) exposure. To investigate the cause of a life-threatening
Victoria Arrandale et al.
International archives of occupational and environmental health, 86(2), 167-175 (2012-03-14)
Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory
Ying-Yu Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(11), 3721-3729 (2013-02-28)
The purpose of this study is to develop an injectable thermoresponsive hydrogel system that can undergo sol-gel phase transition by the stimulation of body temperature with improved mechanical stability and biocompatibility as a controlled drug delivery carrier for cancer therapy.
Coralie F Daussy et al.
Journal of virology, 95(3) (2020-11-20)
Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ASC (apoptosis-associated speck-like protein containing a caspase activation and
Sander M van Putten et al.
Journal of biomedical materials research. Part A, 98(4), 527-534 (2011-06-18)
Biomaterials are at continuous risk of bacterial contamination during production and application. In vivo, bacterial contamination of biomaterials delays the foreign body reaction (FBR). Endotoxins such as lipopolysaccharides (LPS), major constituents of the bacterial cell wall, are potent stimulators of

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