56759
Atto 425
BioReagent, suitable for fluorescence
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关于此项目
经验公式（希尔记法）:
C22H27NO6
CAS Number:
分子量:
401.45
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥90% (HPLC)
表单
(Report result)
制造商/商品名称
ATTO-TEC GmbH
透射比
254 nm, >90%
425 nm, >90%
荧光
λex 440 nm; λem 484 nm
λ
in PBS, pH 7.4
in ethanol (with 0.1% trifluoroacetic acid)
紫外吸收
λ: 423-429 nm Amax
适用性
suitable for fluorescence
运输
wet ice
储存温度
−20°C
SMILES字符串
CCOC(=O)C1=Cc2cc3C(C)CC(C)(C)N(CCCC(O)=O)c3cc2OC1=O
InChI
1S/C22H27NO6/c1-5-28-20(26)16-10-14-9-15-13(2)12-22(3,4)23(8-6-7-19(24)25)17(15)11-18(14)29-21(16)27/h9-11,13H,5-8,12H2,1-4H3,(H,24,25)
InChI key
WNDDWSAHNYBXKY-UHFFFAOYSA-N
应用
Atto 荧光标记专门设计用于高灵敏度应用，包括单分子检测。Atto 标记具有刚性结构，不显示任何顺反异构化。因此，这些标记物在偶联时显示出极低的光谱偏移和异常的强度。Atto 425 适合于制备荧光标记试剂。
法律信息
本产品仅供研究使用。如果打算商业化，请联系知识产权持有者（德国ATTO-TEC GmbH公司）申请许可。
储存分类代码
11 - Combustible Solids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Anna I Sulatskaya et al.
The journal of physical chemistry. B, 116(8), 2538-2544 (2012-01-25)
Benzothiazole dye thioflavin T (ThT) is a sensitive probe for amyloid fibril detection. The ThT probing is based on its unique ability to form highly fluorescent complexes with amyloid and amyloid-like fibrils. In this work we propose an approach of
Katrin G Heinze et al.
Biophysical journal, 86(1 Pt 1), 506-516 (2003-12-26)
Confocal fluorescence spectroscopy is a versatile method for studying dynamics and interactions of biomolecules in their native environment with minimal interference with the observed system. Analyzing coincident fluctuations induced by single molecule movement in spectrally distinct detection channels, dual-color fluorescence
Triple FRET: a tool for studying long-range molecular interactions.
Elke Haustein et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 4(7), 745-748 (2003-08-07)
Irina M Kuznetsova et al.
PloS one, 7(2), e30724-e30724 (2012-03-03)
A new approach for the determination of the amyloid fibril - thioflavin T (ThT) binding parameters (the number of binding modes, stoichiometry, and binding constants of each mode) is proposed. This approach is based on the absorption spectroscopy determination of
Frequency domain fluorescence microspectrometry: Application to cellular uptake and drug distribution.
Praus, P., et al.
Spectroscopy: An International Journal, 24, 303-307 (2010)
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