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Merck
CN

56962

D-myo-Inositol 1,2,4,5,6-pentakis-phosphate

≥96% (HPLC)

别名:

L-myo-Inositol 2,3,4,5,6-pentakis-phosphate

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关于此项目

经验公式(希尔记法):
C6H17O21P5
化学文摘社编号:
分子量:
580.06
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
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assay

≥96% (HPLC)

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O

InChI

1S/C6H17O21P5/c7-1-2(23-28(8,9)10)4(25-30(14,15)16)6(27-32(20,21)22)5(26-31(17,18)19)3(1)24-29(11,12)13/h1-7H,(H2,8,9,10)(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)(H2,20,21,22)/t1-,2-,3-,4+,5-,6-/m1/s1

InChI key

CTPQAXVNYGZUAJ-XCMZKKERSA-N

Biochem/physiol Actions

Important intermediate in inositol phosphate metabolism. Inositides have an important impact on diverse areas of cellular regulation.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Samuel E K Caddick et al.
FEBS letters, 582(12), 1731-1737 (2008-04-30)
We describe a multifunctional inositol polyphosphate kinase/phosphotransferase from Solanum tuberosum, StITPKalpha (GenBank accession number: EF362784), hereafter called StITPK1. StITPK1 displays inositol 3,4,5,6-tetrakisphosphate 1-kinase activity: K(m) = 27 microM, and V(max) = 19 nmol min(-1) mg(-1). The enzyme displays inositol 1,3,4,5,6-pentakisphosphate
Andrew M Riley et al.
Chembiochem : a European journal of chemical biology, 7(7), 1114-1122 (2006-06-07)
myo-Inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P(5)), an inositol polyphosphate of emerging significance in cellular signalling, and its C-2 epimer scyllo-inositol pentakisphosphate (scyllo-InsP(5)) were synthesised from the same myo-inositol-based precursor. Potentiometric and NMR titrations show that both pentakisphosphates undergo a conformational ring-flip at higher
Sandrine Deleu et al.
FEBS letters, 580(7), 1709-1715 (2006-02-28)
Studies [Zhou, D., Chen, L.-M., Hernandez, L., Shears, S.B., and Galán, J.E. (2001) A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host-cell actin cytoskeleton rearrangements and bacterial internalization. Mol. Microbiol. 39, 248-259] with engineered Salmonella