56962
D-myo-Inositol 1,2,4,5,6-pentakis-phosphate
≥96% (HPLC)
别名:
L-myo-Inositol 2,3,4,5,6-pentakis-phosphate
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关于此项目
经验公式（希尔记法）:
C6H17O21P5
化学文摘社编号:
分子量:
580.06
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
InChI
1S/C6H17O21P5/c7-1-2(23-28(8,9)10)4(25-30(14,15)16)6(27-32(20,21)22)5(26-31(17,18)19)3(1)24-29(11,12)13/h1-7H,(H2,8,9,10)(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)(H2,20,21,22)/t1-,2-,3-,4+,5-,6-/m1/s1
SMILES string
O[C@H]1[C@@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O
InChI key
CTPQAXVNYGZUAJ-XCMZKKERSA-N
assay
≥96% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Important intermediate in inositol phosphate metabolism. Inositides have an important impact on diverse areas of cellular regulation.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Degradation of myo-inositol hexakisphosphate by a phytate-degrading enzyme from Pantoea agglomerans.
Ralf Greiner
The protein journal, 23(8), 577-585 (2005-01-15)
High-pressure liquid chromatography (HPLC) analysis established myo-inositol pentakisphosphate as the final product of phytate dephosphorylation by the phytate-degrading enzyme from Pantoea agglomerans. Neither product inhibition by phosphate nor inactivation of the Pantoea enzyme during the incubation period were responsible for
Nathalie Hayez et al.
Journal of neuroimmunology, 149(1-2), 167-181 (2004-03-17)
The neuropeptides Vasoactive-intestinal peptide (VIP) and Pituitary adenylate-cyclase activating protein (PACAP) increased cAMP levels in three out of five human myeloid leukemic cell lines tested while an increased in calcium intracytoplasmic levels was seen only in one cell line (HEL).
Sean G Jackson et al.
BMC structural biology, 11, 11-11 (2011-02-12)
PH domains represent one of the most common domains in the human proteome. These domains are recognized as important mediators of protein-phosphoinositide and protein-protein interactions. Phosphoinositides are lipid components of the membrane that function as signaling molecules by targeting proteins
Laura B Sheard et al.
Nature, 468(7322), 400-405 (2010-10-12)
Jasmonates are a family of plant hormones that regulate plant growth, development and responses to stress. The F-box protein CORONATINE INSENSITIVE 1 (COI1) mediates jasmonate signalling by promoting hormone-dependent ubiquitylation and degradation of transcriptional repressor JAZ proteins. Despite its importance
Samuel E K Caddick et al.
FEBS letters, 582(12), 1731-1737 (2008-04-30)
We describe a multifunctional inositol polyphosphate kinase/phosphotransferase from Solanum tuberosum, StITPKalpha (GenBank accession number: EF362784), hereafter called StITPK1. StITPK1 displays inositol 3,4,5,6-tetrakisphosphate 1-kinase activity: K(m) = 27 microM, and V(max) = 19 nmol min(-1) mg(-1). The enzyme displays inositol 1,3,4,5,6-pentakisphosphate
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