72335
9-(2,2-二氰乙烯基)久洛啶
BioReagent, suitable for fluorescence, ≥97.0% (HPLC)
别名:
9-久洛啶基亚甲基丙二腈, DCVJ
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关于此项目
经验公式（希尔记法）:
C16H15N3
化学文摘社编号:
分子量:
249.31
Beilstein:
413882
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥97.0% (HPLC)
表单
crystals
溶解性
DMSO: soluble
chloroform: soluble
荧光
λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol
适用性
suitable for fluorescence
SMILES字符串
N#C\C(=C/c1cc2CCCN3CCCc(c1)c23)C#N
InChI
1S/C16H15N3/c17-10-13(11-18)7-12-8-14-3-1-5-19-6-2-4-15(9-12)16(14)19/h7-9H,1-6H2
InChI key
LROAUBRDKLVBCP-UHFFFAOYSA-N
包装
无底玻璃瓶。内容物在插入式融锥内。
其他说明
作为荧光探针，用于结合蛋白质等，通过减少自由旋转来增加量子产率；吸收波长在~450nm处，发射波长在480-505nm处（溶剂dep.）
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Christian Lubich et al.
Pharmaceutical research, 32(9), 2863-2876 (2015-03-20)
Sub-visible particles were shown to facilitate unwanted immunogenicity of protein therapeutics. To understand the root cause of this phenomenon, a comprehensive analysis of these particles is required. We aimed at establishing a flow-cytometry-based technology to analyze the amount, size distribution
T Furuno et al.
Immunology letters, 33(3), 285-288 (1992-08-01)
A confocal fluorescence microscope was used to study the exocytotic secretory processes of mast cells in combination with an fluorescent molecular rotor, 9-(dicyanovinyl)julolidine (DCVJ). DCVJ is known to be an unique fluorescent dye which increases its quantum yield with decreasing
C E Kung et al.
Biochemistry, 28(16), 6678-6686 (1989-08-08)
9-(Dicyanovinyl)julolidine (DCVJ) is a fluorescent dye whose intramolecular rotational relaxation is solvent dependent. Since its quantum yield increases with decreasing free volume, this molecule has been very useful in monitoring synthetic polymer reactions and measuring local microviscosity changes in phospholipid
Markus J Schmidt et al.
Journal of biological engineering, 11, 24-24 (2017-08-09)
The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a previously reported photoisomeric behavior may contribute to the measured fluorescence intensity
T Iio et al.
Journal of biochemistry, 109(4), 499-502 (1991-04-01)
A molecular rotor, 9-(dicyanovinyl)julolidine (DCVJ), is a fluorescent dye whose intramolecular rotation determines its fluorescence yield [Kung, C.E. & Reed, J.K. (1989) Biochemistry 28, 6678-6686]. DCVJ binds to bovine brain calmodulin and emits strong fluorescence. In fluorescence titration experiments, the
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