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Merck
CN

82415

Sigma-Aldrich

Prunetin

≥98.0% (TLC)

别名:

4′,5-Dihydroxy-7-methoxyisoflavone

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关于此项目

经验公式(希尔记法):
C16H12O5
化学文摘社编号:
分子量:
284.26
Beilstein:
292155
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
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质量水平

方案

≥98.0% (TLC)

表单

powder

SMILES字符串

COc1cc(O)c2C(=O)C(=COc2c1)c3ccc(O)cc3

InChI

1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key

KQMVAGISDHMXJJ-UHFFFAOYSA-N

生化/生理作用

Inhibitor of both cytoplasmic and mitochondrial human liver aldehyde dehydrogenases, possibly by binding at an allosteric site.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M L Shen et al.
Journal of the American Society for Mass Spectrometry, 12(1), 97-104 (2001-01-06)
Aldehyde dehydrogenases (ALDH) are a family of enzymes primarily involved in the oxidation of various aldehydes. Most ALDH enzymes derived from mammalian sources have been shown to exist as homotetramers, consisting of four identical subunits of approximately 54 kDa. The
Soon-Sen Leow et al.
Experimental gerontology, 106, 198-221 (2018-03-20)
Palm fruit juice (PFJ) containing oil palm phenolics is obtained as a by-product from oil palm (Elaeis guineensis) fruit milling. It contains shikimic acid, soluble fibre and various phenolic acids including p-hydroxybenzoic acid and three caffeoylshikimic acid isomers. PFJ has
Tae-Gue Ahn et al.
Biochemical pharmacology, 85(10), 1525-1533 (2013-02-27)
Prunetin is an O-methylated isoflavone, which is a type of flavonoid. There are a limited number of reports detailing the biological activities of prunetin. Although an anti-inflammatory effect of prunetin has been reported in vitro, to our knowledge, there have
Jean-Philippe Antignac et al.
Rapid communications in mass spectrometry : RCM, 17(12), 1256-1264 (2003-06-18)
In an international context of promoting scientific research on food safety, the interest in molecules having potential hormonal disrupting effects is growing. While industrial endocrine disruptors (phthalates, alkylphenols, PCBs, etc.) have been studied for several years, natural compounds like phytoestrogens
Ruth N Muchiri et al.
Journal of AOAC International, 103(4), 1160-1166 (2020-11-27)
Extracts of red clover (Trifolium pratense L.) containing estrogenic and pro-estrogenic isoflavones are used in dietary supplements primarily for the management of menopausal symptoms in women. A UHPLC-MS/MS assay was developed and validated for the quantitative analysis of the six

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