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Merck
CN

82660

Sigma-Aldrich

1-Pyrenedecanoic acid

≥98.0% (HPLC), suitable for fluorescence

别名:

10-(1-Pyrenyl)decanoic acid

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关于此项目

经验公式(希尔记法):
C26H28O2
化学文摘社编号:
分子量:
372.50
Beilstein:
2007670
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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方案

≥98.0% (HPLC)

表单

powder

荧光

λex 340 nm; λem 376 nm in methanol

适用性

suitable for fluorescence

SMILES字符串

OC(=O)CCCCCCCCCc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C26H28O2/c27-24(28)12-7-5-3-1-2-4-6-9-19-13-14-22-16-15-20-10-8-11-21-17-18-23(19)26(22)25(20)21/h8,10-11,13-18H,1-7,9,12H2,(H,27,28)

InChI key

PIMKEUIWMFJVNB-UHFFFAOYSA-N

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包装

Bottomless glass bottle. Contents are inside inserted fused cone.

分析说明

In addition to the emission maximum at 376 nm, there are lower maxima at 396, 415 and 440 nm.

其他说明

Anionic membrane probe; Measurement of membrane fluidity of polymorphonuclear leukocytes by flow cytometry; Biosynthetically incorporated into cultured fibroblasts

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Radom et al.
Biochimica et biophysica acta, 920(2), 131-139 (1987-07-31)
The lipid metabolism in cultured fibroblasts from multisystemic (type 3) lipid storage myopathy and controls has been studied through pulse-chase experiments using 1-pyrenedecanoic acid as precursor. The uptake of 1-pyrenedecanoic acid was not significantly different in multisystemic lipid storage myopathy
M Masuda et al.
Journal of immunological methods, 96(2), 225-231 (1987-02-11)
A method was established for measuring membrane fluidity of polymorphonuclear leukocytes (PMN) by the excimer-forming lipid technique with pyrenedecanoic acid in flow cytometry. When cells were labeled, the use of 2-25 microM of pyrenedecanoic acid provided similar results. Neither the
Pyrenedecanoic acid and pyrene lecithin.
H J Galla et al.
Methods in enzymology, 72, 471-479 (1981-01-01)
Taro Yasumoto et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(8), 9220-9234 (2019-05-16)
Amyloid β-protein (Aβ) molecules tend to aggregate and subsequently form low MW (LMW) oligomers, high MW (HMW) aggregates such as protofibrils, and ultimately fibrils. These Aβ species can generally form amyloid plaques implicated in the neurodegeneration of Alzheimer disease (AD)
Amit K Saha et al.
Biophysical journal, 112(7), 1481-1488 (2017-04-14)
Cholesterol is an important risk factor of atherosclerosis, due to its active uptake by monocytes/macrophages. Monocyte recruitment from flowing blood to atherosclerotic foci is the key first step in the development of atherosclerosis. Cholesterol content alters cell membrane stiffness, and

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