85555
大观霉素 二盐酸盐 五水合物
≥98.0% (AT)
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H24N2O7 · 2HCl · 5H2O
化学文摘社编号:
分子量:
495.35
Beilstein:
5684150
EC 号:
MDL编号:
UNSPSC代码:
51101500
PubChem化学物质编号:
生物来源
synthetic
方案
≥98.0% (AT)
表单
solid
颜色
white
溶解性
H2O: 50 mg/mL, clear, faintly yellow
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
protein synthesis | interferes
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2
InChI
1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
InChI key
DCHJOVNPPSBWHK-UXXUFHFZSA-N
正在寻找类似产品? 访问 产品对比指南
一般描述
Chemical structure: aminoglycoside
应用
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
制备说明
Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.
其他说明
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.
免责声明
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Corinna Kehrenberg et al.
Antimicrobial agents and chemotherapy, 51(6), 2244-2246 (2007-03-21)
Pasteurella multocida isolates with high-level spectinomycin resistance in which no adenyltransferase genes could be demonstrated exhibited a C1192G transversion in the 16S rRNA of all six or five of the six rRNA operons and/or two different types of 3-bp deletions
D Moazed et al.
Nature, 327(6121), 389-394 (1987-06-04)
Chemical footprinting shows that several classes of antibiotics (streptomycin, tetracycline, spectinomycin, edeine, hygromycin and the neomycins) protect concise sets of highly conserved nucleotides in 16S ribosomal RNA when bound to ribosomes. These findings have strong implications for the mechanism of
Daniel Criswell et al.
Antimicrobial agents and chemotherapy, 50(2), 445-452 (2006-01-27)
We have isolated and characterized in vitro mutants of the Lyme disease agent Borrelia burgdorferi that are resistant to spectinomycin, kanamycin, gentamicin, or streptomycin, antibiotics that target the small subunit of the ribosome. 16S rRNA mutations A1185G and C1186U, homologous
Nicholas Desnoyer et al.
BMC plant biology, 20(1), 380-380 (2020-08-20)
Glycosylphosphatidylinositol (GPI) addition is one of the several post-translational modifications to proteins that increase their affinity for membranes. In eukaryotes, the GPI transamidase complex (GPI-T) catalyzes the attachment of pre-assembled GPI anchors to GPI-anchored proteins (GAPs) through a transamidation reaction.
John R Waldeisen et al.
PloS one, 6(12), e28528-e28528 (2011-12-14)
Current molecular diagnostic techniques for susceptibility testing of septicemia rely on genotyping for the presence of known resistance cassettes. This technique is intrinsically vulnerable due to the inability to detect newly emergent resistance genes. Traditional phenotypic susceptibility testing has always
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持