A0638
己二酸二酰肼
≥98% (titration)
别名:
Hexanedihydrazide
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
线性分子式:
NH2NHCO(CH2)4CONHNH2
化学文摘社编号:
分子量:
174.20
UNSPSC Code:
12352127
NACRES:
NA.25
PubChem Substance ID:
EC Number:
213-999-5
Beilstein/REAXYS Number:
973863
MDL number:
Quality Level
assay
≥98% (titration)
form
powder
reaction suitability
reagent type: cross-linking reagent
mp
180-182 °C (lit.)
solubility
H2O: 100 mg/mL
storage temp.
−20°C
SMILES string
NNC(=O)CCCCC(=O)NN
InChI
1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)
InChI key
IBVAQQYNSHJXBV-UHFFFAOYSA-N
General description
己二酸二酰肼是一种同型双功能交联剂，对醛具有特异性。因而腙键相对稳定。在高碘酸盐氧化后，己二酸二酰肼常用于位点特异性连接各类糖蛋白，如抗体。低pKa的酰肼可避免与伯胺竞争，因此可在pH 5.0条件下进行氧化和偶联。
Application
己二酸二酰肼已用于：
- 制备反应性预混物，合成多孔生物材料
- 交联甲基丙烯酸化硫酸软骨素 (MA-CS) 涂层，利用基于碳二亚胺的化学方法生产和表征甲基丙烯酸化硫酸软骨素磁性纳米粒子(MA-CS MNPs)
- 使用Abberior STARNHS酯染料共价标记鼠李糖脂、绿脓杆菌素和万古霉素
Biochem/physiol Actions
己二酸二酰肼(ADH)是一种低分子量化合物，每个末端都包含一个酰肼基团。这可为重金属提供额外的吸附位点，从而维持或提高交联吸附剂的吸附能力。ADH可用作多个领域的交联剂，如制造机械乳胶膜和可注射氧化透明质酸水凝胶。
Other Notes
请注意联氨键可以通过选择性还原来稳定，例如使用氰化钠。
Still not finding the right product?
Explore all of our products under 己二酸二酰肼
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Bartosz Gerard Gdaniec et al.
iScience, 25(1), 103669-103669 (2022-01-15)
Efficient delivery of toxic compounds to bacterial competitors is essential during interspecies microbial warfare. Rhamnolipids (RLPs) are glycolipids produced by Pseudomonas and Burkholderia species involved in solubilization and uptake of environmental aliphatic hydrocarbons and perform as biosurfactants for swarming motility.
Tulsidas G Shrivastav et al.
Journal of immunoassay & immunochemistry, 33(1), 1-17 (2011-12-21)
The introduction of spacers in coating steroid antigen or enzyme conjugates or immunogen is known to exert an influence on the sensitivity of steroid enzyme immunoassays. We have introduced different homobifunctional spacers having varying atomic length (3 to 10) between
U Heimgartner et al.
The Biochemical journal, 267(3), 585-591 (1990-05-01)
After periodate oxidation and incubation with a dihydrazide, cross-linking of the two heavy chains of immunoglobulins G from several species proceeds specifically through their oligosaccharides. We have used malonic acid dihydrazide, adipic acid dihydrazide and dithiodipropionic acid dihydrazide. The last
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A0638-100G | 04061835326204 |
| A0638-25G | 04061833334201 |