A7655
阿替洛尔
≥98% (TLC), powder, β₁-adrenoceptor antagonist
别名:
(±)-4-[2-羟基-3-[（1-甲基乙基）氨基] 丙氧基] 苯乙酰胺, 4-[2′-羟基-3′-（异丙胺基）丙氧基] 苯乙酰胺
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关于此项目
经验公式（希尔记法）:
C14H22N2O3
化学文摘社编号:
分子量:
266.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
249-451-7
MDL number:
产品名称
阿替洛尔, ≥98% (TLC), powder
Quality Level
assay
≥98% (TLC)
form
powder
color
white to off-white
solubility
H2O: 0.3 mg/mL, DMSO: 18 mg/mL, ethanol: 3.4 mg/mL
originator
AstraZeneca
SMILES string
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
InChI
1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
InChI key
METKIMKYRPQLGS-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153)
rat ... Adrb1(24925)
Application
阿替洛尔是一种 β 肾上腺素能受体阻断药，用于治疗高血压。阿替洛尔具有抗心绞痛和抗心律失常的作用。
Biochem/physiol Actions
选择性 β1 肾上腺素受体拮抗剂；抗高血压；抗心绞痛；抗心律失常。
Features and Benefits
该化合物由 AstraZeneca 公司开发。若要浏览其他制药公司研发的化合物和批准的药物/候选药物列表，请单击此处。
Other Notes
固体的有效期至少为 3 年。
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
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Ronald V Lacro et al.
The New England journal of medicine, 371(22), 2061-2071 (2014-11-19)
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A7655-10G | 04061832269078 |
| A7655-1G | 04061833386040 |
| A7655-25G | 04061832088716 |
| A7655-5G | 04061833386057 |