A9165

N-乙酰基-L-半胱氨酸

Name: <I>N</I>-乙酰基-<SC>L</SC>-半胱氨酸
Brand: SIGMA

≥99% (TLC), suitable for cell culture, BioReagent

别名:

LNAC, NAC

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线性分子式:

HSCH₂CH(NHCOCH₃)CO₂H

化学文摘社编号:

616-91-1

分子量:

163.19

NACRES:

NA.26

PubChem Substance ID:

24891402

UNSPSC Code:

12352209

EC Number:

210-498-3

MDL number:

MFCD00004880

Beilstein/REAXYS Number:

1724426

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产品名称

N-乙酰基-L-半胱氨酸, suitable for cell culture, BioReagent

product line

BioReagent

Quality Level

200

assay

≥99% (TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

106-108 °C (lit.)

solubility

H₂O: 100 mg/mL (with heating)

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

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Application

N-乙酰-L-半胱氨酸已被用作小鼠肠道干细胞培养的肠道基础培养基的组成部分，也被用作膨胀培养基的组成部分。

Biochem/physiol Actions

抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。据报道可防止神经细胞凋亡，但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

存储类别

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Derivation and long-term expansion of human endometrial and decidual organoids

Margherita Turco

Protocol Exchange, 2639-2644 (2017)

Isolation, Culture, and Maintenance of Mouse Intestinal Stem Cells

Kevin P. O?Rourke

Bio-protocol, 6(4), e1733-e1733 (2016)

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Meritxell Huch et al.

Nature, 494(7436), 247-250 (2013-01-29)

The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem

Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells.

Suzanne M Cloonan et al.

Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)

Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that

The chemistry and biological activities of N-acetylcysteine.

Yuval Samuni et al.

Biochimica et biophysica acta, 1830(8), 4117-4129 (2013-04-27)

N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion cardiac injury, acute respiratory distress syndrome, bronchitis, chemotherapy-induced toxicity

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Mitochondrial Stress and ROS

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L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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全球贸易项目编号

货号	GTIN
A9165-100G	04061833401392
A9165-25G	04061833401408
A9165-5G	04061833401415

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N-乙酰基-L-半胱氨酸

≥99% (TLC), suitable for cell culture, BioReagent

选择尺寸

关于此项目

主要文件

属性

产品名称

product line

Quality Level

assay

form

technique(s)

color

mp

solubility

storage temp.

SMILES string

InChI

InChI key

相关类别

说明

Application

Biochem/physiol Actions

Other Notes

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

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