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Merck
CN

B1552

溴烯醇内酯

≥98% (TLC)

别名:

BEL, E-6-(溴乙烯)四氢-3-(1-萘基)-2H-吡喃-2-酮

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关于此项目

经验公式(希尔记法):
C16H13BrO2
化学文摘社编号:
分子量:
317.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Quality level:
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biological source

synthetic (organic)

Quality Level

assay

≥98% (TLC)

form

powder

potency

636 nM Ki

solubility

DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.), degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)

λmax

224 nm

storage temp.

−20°C

SMILES string

[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23

InChI

1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+

InChI key

BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Biochem/physiol Actions

来自P388D巨噬细胞(IC 50 = 8μM)的钙取代磷脂酶A2和镁取代磷脂酸磷酸磷酸酶的强效,不可逆抑制剂;酶激活的不可逆糜蛋白酶抑制剂(K i = 636 nM)。

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ulrika Christerson et al.
Cells, 8(7) (2019-07-07)
Increased activity of secretory phospholipases A2 (sPLA2) type-II was previously observed in ileum of Crohn's disease (CD). Our aims were to explore the involvement of calcium-independent (i)PLA2β in the release of sPLA2s from the human mast cell (MC) line (HMC-1)
Masahiro Nagahama et al.
Toxins, 10(5) (2018-05-23)
Clostridium perfringens iota-toxin is a binary actin-ADP-ribosylating toxin composed of the enzymatic component Ia and receptor binding component Ib. Ib binds to a cell surface receptor, forms Ib oligomer in lipid rafts, and associates with Ia. The Ia-Ib complex then
Kasey K Pham et al.
Genome, 60(9), 720-732 (2017-04-27)
Owing to high rates of introgressive hybridization, the plastid genome is poorly suited to fine-scale DNA barcoding and phylogenetic studies of the oak genus (Quercus, Fagaceae). At the tips of the oak plastome phylogeny, recent gene migration and reticulation generally
C D Eiber et al.
Vision research, 151, 41-52 (2017-11-14)
The "blue-on" and "blue-off" receptive fields in retina and dorsal lateral geniculate nucleus (LGN) of diurnal primates combine signals from short-wavelength sensitive (S) cone photoreceptors with signals from medium/long wavelength sensitive (ML) photoreceptors. Three questions about this combination remain unresolved.
Sunbin Ling et al.
Molecular oncology, 11(6), 682-695 (2017-04-19)
Drug treatments for hepatocellular carcinoma (HCC) often fail because of multidrug resistance (MDR). The mechanisms of MDR are complex but cancer stem cells (CSCs), which are able to self-renew and differentiate, have recently been shown to be involved. The deubiquitinating

商品

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

全球贸易项目编号

货号GTIN
B1552-5MG04061833258651

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