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关于此项目
经验公式(希尔记法):
C23H25N5O4 · HCl
化学文摘社编号:
分子量:
471.94
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
MDL number:
产品名称
Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride, protease substrate
Quality Level
assay
≥99% (TLC)
form
powder
solubility
DMSO:methanol (1:1): 20 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@H](CCCNC(N)=N)NC(=O)c3ccccc3)ccc12
InChI
1S/C23H25N5O4.ClH/c1-14-12-20(29)32-19-13-16(9-10-17(14)19)27-22(31)18(8-5-11-26-23(24)25)28-21(30)15-6-3-2-4-7-15;/h2-4,6-7,9-10,12-13,18H,5,8,11H2,1H3,(H,27,31)(H,28,30)(H4,24,25,26);1H/t18-;/m0./s1
InChI key
XKAVYOJOHZLTDF-FERBBOLQSA-N
General description
A sensitive fluorogenic substrate for papain and trypsin.
Application
Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride has been used:
- as a substrate for trypsin-like proteolysis of peptide in red blood cells
- as a substrate for midgut proteases of Pieris brassicae
- as a substrate in screening serine protease activity of venom
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Uncover properties and applications of the cysteine protease papain and find inhibitors, substrates, and other papain products.
木瓜蛋白酶是肽酶C1家族的一种半胱氨酸蛋白酶。它由单一多肽链组成,含有三个二硫键和一个酶活性所必需的巯基。
Trypsin-like proteolytic contamination of commercially available psa purified from human seminal fluid
Manning ML, et al.
Prostate, 72(11), 1233-1238 (2012)
Purification and functional characterisation of rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros
Vaiyapuri S, et al.
Testing, 5(3), e9687-e9687 (2010)
Carmen Navarro-Guillén et al.
PloS one, 16(4), e0248356-e0248356 (2021-04-10)
New and more efficient methods to sustainably intensify Aquaculture production are essential to attain the seafood demand for direct human consumption in the near future. Nutrition has been identified as one strategy of early exposure that might affect animal early
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B7260-5MG | 04061833441619 |
| B7260-25MG | 04061833441602 |