C3050
头孢菌素 钠盐
BioReagent, suitable for cell culture
别名:
7-(2-Thienylacetamido)cephalosporanic acid sodium salt, Cephalotin sodium salt
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关于此项目
经验公式（希尔记法）:
C16H15N2NaO6S2
化学文摘社编号:
分子量:
418.42
EC Number:
200-394-6
UNSPSC Code:
51101500
PubChem Substance ID:
Beilstein/REAXYS Number:
4120706
MDL number:
product line
BioReagent
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
water: 50 mg/mL, clear, colorless to light yellow
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O
InChI
1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1
InChI key
VUFGUVLLDPOSBC-XRZFDKQNSA-M
General description
Cephalotin is a first generation cephalosporin antibiotic.
Chemical structure: β-lactam
Biochem/physiol Actions
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.
Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.
Mode of Resistance: Production of cephalosporinase will inactivate the product.
Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.
Mode of Resistance: Production of cephalosporinase will inactivate the product.
Mode of Action: Inhibits cell wall synthesis.
Antimicrobial spectrum: Gram-positive cocci.
Mode of Resistance: Cephalosporinase production.
Antimicrobial spectrum: Gram-positive cocci.
Mode of Resistance: Cephalosporinase production.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Esteban C Nannini et al.
Antimicrobial agents and chemotherapy, 54(5), 2206-2208 (2010-03-10)
Using 98 clinical methicillin-susceptible Staphylococcus aureus isolates of known beta-lactamase (Bla) type, we found a pronounced inoculum effect for cephalexin (mostly Bla type A and C strains), a mild inoculum effect for cephalothin (especially types B and C), and no
Chun-Hsien Lin et al.
Peptides, 36(1), 114-120 (2012-05-09)
The in vitro activity of mastoparan-AF, an amphipathic antimicrobial peptide isolated from the hornet venom of Vespa affinis, alone and in combination with various clinically used antibiotics, was investigated against 21 Escherichia coli isolates/strains. Most E. coli isolates tested were
Gunnar Baatrup et al.
BMC surgery, 9, 17-17 (2009-12-09)
The antibiotics used for prophylaxis during surgery may influence the rate of surgical site infections. Tetracyclines are attractive having a long half-life and few side effects when used in a single dose regimen. We studied the rate of surgical site