C3633
DL-胱硫醚
≥90% (HPLC)
别名:
半胱氨酸, S-(2-氨基-2-甲酸基乙基)高半胱氨酸
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关于此项目
线性分子式:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
化学文摘社编号:
分子量:
222.26
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
208-613-7
MDL number:
产品名称
DL-胱硫醚, ≥90% (HPLC)
InChI key
ILRYLPWNYFXEMH-UHFFFAOYSA-N
InChI
1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
SMILES string
NC(CCSCC(N)C(O)=O)C(O)=O
assay
≥90% (HPLC)
form
powder
color
white to off-white
mp
281 °C (dec.)
storage temp.
2-8°C
Quality Level
Gene Information
human ... BHMT(635)
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Biochem/physiol Actions
胱硫醚是氨基酸半胱氨酸生物合成的一种中间体。胱硫醚可作为底物用于区分和分析胱硫醚γ-裂合酶。
Preparation Note
由Stekol法制备。
Other Notes
4种立体异构体的混合物；L-, D-, L-allo-和D-allo-胱硫醚。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Miriam M Cortese-Krott et al.
Antioxidants & redox signaling, 27(10), 684-712 (2017-04-12)
Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances:
A new synthesis of S-(beta-amino-beta-carboxyethyl) homocysteine (cystathionine) and S-bis(gamma-amino-gamma -carboxypropyl) sulfide (homolanthionine).
J A STEKOL
The Journal of biological chemistry, 173(1), 153-157 (1948-03-01)
Zhi-Jun Wang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(3), 859-875 (2017-06-24)
Hydrogen sulfide (H2S) is now admitted as a third gasotransmitter together with nitric oxide (NO) and carbon monoxide (CO), albeit it was originally considered as a foul and poisonous gas. Endogenous H2S production in mammalian cells is counting on the
Hydrogen Sulfide Inhibits Cigarette Smoke-Induced Endoplasmic Reticulum Stress and Apoptosis in Bronchial Epithelial Cells.
Fan Lin et al.
Frontiers in pharmacology, 8, 675-675 (2017-10-17)
Qinghai Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(6), 2200-2213 (2018-09-27)
The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular endothelial cell dysfunction. Hydrogen sulfide (H2S) has been shown to have an anti-oxidative effect, but its mode
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