Anti-Calcium Channel Ca_V3.3 (α_1I) antibody produced in rabbit

Calcium channel CaV3.3 (α1I) is a low-voltage-activated T-type calcium channel. CaV3.3 (α1I) transcripts are detected in central nervous system as well as thyroid and adrenal glands.

peptide corresponding to amino acid residues 1053-1067 of rat Ca_V3.3. Homology with other species: human is 14/15 residues identical.

Anti-Calcium Channel CaV3.3 (a1I) antibody produced in rabbit is suitable for western blot at a dilution of 1:200 using rat brain membranes.

Calcium channel CaV3.3 (α1I) is involved in neuronal excitability and is particularly recruited during the depolarizing after-potential. It is responsible for generating sustained electrical activity. Sperm specific proteins CatSper1 and CatSper2 interact with Cav3.3 and suppress Cav3.3-evoked T-type calcium channel activity.

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

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