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C5151

3-氨基甲酰-PROXYL

Name: 3-氨基甲酰-PROXYL
Brand: SIGMA

别名:

3-氨基甲酰-2,2,5,5-四甲基-1-吡咯烷氧基, 3-氨基甲酰-2,2,5,5-四甲基四氢吡咯氮氧自由基

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关于此项目

经验公式（希尔记法）:

C₉H₁₇N₂O₂

化学文摘社编号:

4399-80-8

分子量:

185.24

NACRES:

NA.22

PubChem Substance ID:

24892761

UNSPSC Code:

12352000

EC Number:

224-533-5

MDL number:

MFCD00003168

Form:

powder

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Quality Level

100

form

powder

mp

173-175 °C (lit.)

storage temp.

2-8°C

SMILES string

CC1(C)CC(C(N)=O)C(C)(C)N1[O]

InChI

1S/C9H17N2O2/c1-8(2)5-6(7(10)12)9(3,4)11(8)13/h6H,5H2,1-4H3,(H2,10,12)

InChI key

XNNPAWRINYCIHL-UHFFFAOYSA-N

Application

自旋标记物，用于通过电子自旋共振成像进行自由基的体内无创检测。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

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Measurements of UV-generated free radicals/reactive oxygen species (ROS) in skin.

Th Herrling et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 63(4), 840-845 (2006-03-18)

Free radicals/reactive oxygen species (ROS) generated in skin by UV irradiation were measured by electron spin resonance (ESR). To increase the sensitivity of measurement the short life free radicals/ROS were scavenged and accumulated by using the nitroxyl probe 3-carboxy-2,2,5,5-tetrametylpyrrolidine-1-oxyl (PCA).

Neuroprotection by the stable nitroxide 3-carbamoyl-proxyl during reperfusion in a rat model of transient focal ischemia.

Guohan Hu et al.

Journal of neurosurgery, 98(2), 393-396 (2003-02-21)

Nitroxides mimic superoxide dismutase (SOD) biochemically and may prevent free radical oxidative injury in settings in which endogenous SOD is overwhelmed. The authors have previously shown the efficacy of a nitroxide, Tempol, in reducing stroke infarct size. Of the nitroxides

High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents.

Ken-Ichiro Matsumoto et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 12(8), 2455-2462 (2006-04-28)

There is considerable research directed toward the identification and development of functional contrast agents for medical imaging that superimpose tissue biochemical/molecular information with anatomical structures. Nitroxide radicals were identified as in vivo radioprotectors. Being paramagnetic, they can provide image contrast

In vivo detection of gastric cancer in rats by electron paramagnetic resonance imaging.

Tomiko Mikuni et al.

Cancer research, 64(18), 6495-6502 (2004-09-18)

Electron paramagnetic resonance imaging (EPRI) enables noninvasive spatial mapping of free radical metabolism and has recently been shown to provide in vivo physiologic information regarding alterations in the redox state of tumors and neoplastic tissues. With the use of nitroxide

Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents.

Fuminori Hyodo et al.

Cancer research, 66(20), 9921-9928 (2006-10-19)

Nitroxide radicals are paramagnetic contrast agents, used in magnetic resonance imaging (MRI), that also exert antioxidant effects. Participating in cellular redox reactions, they lose their ability to provide contrast as a function of time after administration. In this study, the

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全球贸易项目编号

货号	GTIN
C5151-1G	04061826703076

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