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Merck
CN

C5417

β-咔啉-3-羧酸甲酯

别名:

β-CCM, 9H-吡啶并[3,4-b]吲哚-3-羧酸甲酯

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经验公式(希尔记法):
C13H10N2O2
化学文摘社编号:
分子量:
226.23
UNSPSC Code:
12352103
MDL number:
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mp

265 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

COC(=O)c1cc2c(cn1)[nH]c3ccccc23

Biochem/physiol Actions

苯二氮卓反向受体激动剂;致焦虑性;在体内引起癫痫。
苯二氮卓拮抗剂


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K P Lippke et al.
Journal of medicinal chemistry, 26(4), 499-503 (1983-04-01)
Several esters of beta-carboline-3-carboxylic acid were synthesized and tested in respect to their affinity for the benzodiazepine receptor in bovine cortex membranes. Out of these derivatives, the methyl, ethyl, and n-propyl ester were clearly the most potent, while the n-butyl