InChI
1S/C24H40O4.Na.H/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);;/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;;/m1../s1
SMILES string
[Na].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])CC[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O
InChI key
WANBNZVOEKGHSS-VQNKLXGESA-N
description
anionic
assay
≥97%
form
powder
mol wt
414.55 g/mol
technique(s)
protein purification: suitable
Quality Level
General description
鹅去氧胆酸钠是一种胆汁盐,研究已显示其可加速结肠转运并改善肠功能。
Application
鹅去氧胆酸钠已被用于一项研究中,以评估大肠杆菌中的DNA修复反应。它也已被用于一项研究中,以研究影响艰难梭菌 孢子出芽的物理和化学因素。
Biochem/physiol Actions
胆盐
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
L J Wheeldon et al.
Journal of applied microbiology, 105(6), 2223-2230 (2009-01-06)
To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores. Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat or
Sarinya Tawthep et al.
Journal of bioscience and bioengineering, 124(5), 514-522 (2017-07-29)
Understanding the dynamics of secondary bile acid (SBA) formation in the gut by SBA-producing bacteria is important for host health, as SBAs have been shown to affect host pathophysiology and gut microbiota composition. However, our knowledge of SBA producers is
R L Kandell et al.
Nutrition and cancer, 16(3-4), 227-238 (1991-01-01)
Two bile salts, sodium chenodeoxycholate and sodium deoxycholate, induced a DNA repair response in the bacterium Escherichia coli. Similarly, a bile acid and a bile salt, chenodeoxycholic acid and sodium deoxycholate, induced DNA repair (indicated by unscheduled DNA synthesis) in
V Vanhoorne et al.
Orphanet journal of rare diseases, 14(1), 186-186 (2019-08-03)
Pharmaceutical compounding of orphan active ingredients can offer cost-effective treatment to patients when no other drug product is available for a rare disease or during periods of drug product shortages. Additionally, it allows customized therapy for patients with rare diseases.
Tina Kauss et al.
Journal of pharmaceutical sciences, 108(8), 2805-2813 (2019-03-18)
Current pediatric antibiotic therapies often use oral and parenteral routes of administration. Neither are suitable for treating very sick neonates who cannot take oral medication and may be several hours away from hospital in developing countries. Here, we report on
商品
Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.
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