form
acetone suspension
extent of labeling
≥50 μmol per mL
matrix
cross-linked 4% beaded agarose
matrix active group
carbonylimidazole
matrix spacer
1 atom (when ligands are coupled to the carbonyl group by displacement of imidazole)
capacity
10-20 μmol/mL coupling capacity (diaminohexane)
mp
117-122 °C (lit.)
storage temp.
2-8°C
SMILES string
O=C(n1ccnc1)n2ccnc2
InChI
1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
InChI key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
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M T Hearn et al.
Journal of chromatography, 185, 463-470 (1979-12-20)
The use of 1,1'-carbonyldiimidazole-activated agarose for biospecific affinity chromatography is described. Activation of agarose with this carbonylating reagent gives a matrix devoid of additional charged groups. Conditions for the coupling of a range of ligands and leashes have been evaluated.
Marie-José van Hoof et al.
Attachment & human development, 17(4), 354-375 (2015-06-06)
Although attachment representation is considered to be disturbed in traumatized adolescents, it is not known whether this is specific for trauma, as comparative studies with other clinical groups are lacking. Therefore, attachment representation was studied by means of the Adult
Thomas-Xavier Métro et al.
Chemical communications (Cambridge, England), 48(96), 11781-11783 (2012-10-31)
The synthesis of various amides has been realised avoiding the use of any organic solvent from activation of carboxylic acids with CDI to isolation of the amides. Mechanochemistry was the key point of the process allowing rapid formation of the
Hye Jin Lee et al.
Analytical chemistry, 78(18), 6504-6510 (2006-09-15)
This paper describes a simple methodology for the creation of high-density multiplexed antibody arrays on gold surfaces that can be used to detect low molecular weight protein biomarkers with surface plasmon resonance imaging (SPRI). A one-step carbonyldiimidazole (CDI) surface reaction
A Sousa et al.
Journal of chromatography. A, 1218(46), 8333-8343 (2011-10-15)
The growing demand on plasmid DNA (pDNA) manufacture for therapeutic applications requires a final product with higher quality and quantity, spending the least time. Most of the current processes for pDNA production use at least one chromatographic step, which often
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