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G0759

甘氨鹅脱氧胆酸钠

别名:

3α,7α-二羟基-5β-胆烷酸 N-（羧甲基）酰胺 钠盐, N-(3α,7α-二羟基-24-氧代胆烷-24-基)甘氨酸 钠盐, 甘氨鹅脱氧胆酸 钠盐

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关于此项目

经验公式（希尔记法）:
C26H42NNaO5
化学文摘社编号:
16564-43-5
分子量:
471.61
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24895023
MDL number:
MFCD00036743
Beilstein/REAXYS Number:
3847290
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description

anionic

Quality Level

200

form

powder

mol wt

471.61 g/mol

technique(s)

HPLC: suitable, protein quantification: suitable

functional group

sulfonic acid

shipped in

ambient

storage temp.

room temp

SMILES string

[Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/m1./s1

InChI key

AAYACJGHNRIFCT-YRJJIGPTSA-M

General description

甘氨鹅脱氧胆酸盐 (GCDC) 是一种有毒的疏水性胆汁盐。

Application

甘氨鹅去氧胆酸钠已被用作 de Man、Rogosa 和 Sharpe (MRS) 琼脂中的添加剂，用于胆汁酸解偶联，测定菌株解偶联特定胆汁酸的能力。
甘氨鹅脱氧胆酸钠已可用于评估胆汁盐诱导的DNA损伤的修复。 它还被用于研究A型产气荚膜梭菌( Clostridium perfringens ）在人胆汁盐存在下的肠毒素产生。

Biochem/physiol Actions

甘氨鹅脱氧胆酸盐 (GCDC) 可诱导部分由 Fas 介导的肝细胞凋亡。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000558960
0000558961
0000513848
0000513849
0000528519

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实验方案

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

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Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

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全球贸易项目编号

货号GTIN
G0759-500MG04061833624241
G0759-10G04061833624197
G0759-100MG04061833624180
G0759-25MG04061833624234
G0759-25G04061833624227
G0759-1G04061833624210