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线性分子式:
NH2CH2CONHCH(COOH)CH2C6H5
化学文摘社编号:
分子量:
222.24
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
222-027-9
MDL number:
Beilstein/REAXYS Number:
2279318
产品名称
Gly-Phe,
InChI key
JBCLFWXMTIKCCB-VIFPVBQESA-N
InChI
1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1
SMILES string
NCC(=O)N[C@@H](Cc1ccccc1)C(O)=O
assay
≥97.0% (TLC)
form
crystalline
color
white
mp
264 °C
storage temp.
−20°C
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Resolution of chiral compounds by HPLC using mobile phase additives and a porous graphitic carbon stationary phase.
B J Clark et al.
Journal of pharmaceutical and biomedical analysis, 7(12), 1883-1888 (1989-01-01)
J J Sperinde et al.
Bioconjugate chemistry, 10(2), 213-220 (1999-03-17)
Kinetic parameters have been measured for coupled nucleophilic and solvolytic reactions of 2,2,2-trifluoroethanesulfonyl (tresyl)-modified poly(ethylene glycol) based on a system of coupled differential equations implied by recently proposed elementary reaction mechanisms. Fitted kinetic parameters were found to be strong functions
Wutharath Chin et al.
Journal of the American Chemical Society, 127(2), 707-712 (2005-01-13)
Laser desorption of model peptides coupled to laser spectroscopic techniques enables the gas-phase observation of genuine secondary structures of biology. Spectroscopic evidence for the formation of beta-turns in gas-phase peptide chains containing glycine and phenylalanine residues establishes the intrinsic stability
T Takarada et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 6(21), 3906-3913 (2000-12-29)
Oligopeptides are efficiently hydrolyzed by Ce(IV) to the corresponding amino acids under mild conditions. The pseudo first-order rate constants for the hydrolysis of H-Gly-Phe-OH and H-Gly-Gly-OH at pH 7.0 and 50 degrees C are 3.5 x 10(-1) and 2.8 x
Susan Weng Larsen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 22(5), 399-408 (2004-07-22)
Oil-based depot formulations may constitute a future delivery method for small peptides. Thus, a requirement is attainment of sufficient oil solubility for such active compounds. A model dipeptide (Gly-Phe) has been converted into lipophilic prodrugs by esterification at the C-terminal
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