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Merck
CN
所有图片(1)

主要文件

G4541

Sigma-Aldrich

Gly-Gly-His

≥98% (TLC)

别名:

Copper-binding peptide

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About This Item

经验公式(希尔记法):
C10H15N5O4
CAS Number:
分子量:
269.26
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.26

Product Name

Gly-Gly-His,

方案

≥98% (TLC)

质量水平

表单

solid

颜色

white

储存温度

−20°C

InChI

1S/C10H15N5O4/c11-2-8(16)13-4-9(17)15-7(10(18)19)1-6-3-12-5-14-6/h3,5,7H,1-2,4,11H2,(H,12,14)(H,13,16)(H,15,17)(H,18,19)

InChI key

PDAWDNVHMUKWJR-UHFFFAOYSA-N

Amino Acid Sequence

Gly-Gly-His

一般描述

Gly-Gly-His (GGH) tripeptide with carboxyl-terminal histidine residue is hydrophilic.

应用

Gly-Gly-His has been used:
  • as a peptide test probe in the hydrophilic interaction liquid chromatography (HILIC) studies
  • in the electrochemical modification of back-side contact transducers (BSC) electrodes in copper (Cu2+) sensing studies
  • for the fabrication carbon nanotube electrode for detection of Cu2+ ions

生化/生理作用

Gly-Gly-His (GGH) tripeptide displays the affinity of copper (Cu2+) complexation. These complexes display good skin tolerance and may be useful in wound healing. GGH copper complexes are proposed to reduce tumor necrosis factor α (TNF-α)-based interleukin 6 (IL-6) secretion by in vivo studies with fibroblasts. GGH is used in comparative studies with other imidazole-containing peptides such as carnosine. An area of active application research involves the GGH binding of copper ions.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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