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G6013

L -还原型谷胱甘肽

Name: <SC>L </SC>-还原型谷胱甘肽
Brand: SIGMA

≥98.0%, suitable for cell culture, BioReagent

别名:

γ-L-谷酰基-L-半胱氨酰-甘氨酸, GSH

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关于此项目

线性分子式:

H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H

化学文摘社编号:

70-18-8

分子量:

307.32

NACRES:

NA.26

PubChem Substance ID:

24895241

UNSPSC Code:

12352209

EC Number:

200-725-4

MDL number:

MFCD00065939

Beilstein/REAXYS Number:

1729812

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属性

产品名称

L -还原型谷胱甘肽, suitable for cell culture, BioReagent, ≥98.0%, powder

product line

BioReagent

Quality Level

300

assay

≥98.0%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

192-195 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

说明

Application

可在5-10 mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。

Biochem/physiol Actions

作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。经由这些机制，它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

Lot/Batch Number

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