G6132
Glycodeoxycholic acid monohydrate
≥97% (TLC)
别名:
3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
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关于此项目
线性分子式:
C26H43NO5
化学文摘社编号:
分子量:
467.64
PubChem Substance ID:
UNSPSC Code:
12161900
Beilstein/REAXYS Number:
2954947
MDL number:
description
anionic
assay
≥97% (TLC)
SMILES string
[H]O[H].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(=O)NCC(O)=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI
1S/C26H43NO5.H2O/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);1H2/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;/m1./s1
InChI key
DLOTUJUSJVIXDW-YEUHZSMFSA-N
Biochem/physiol Actions
Induces apoptosis in hepatocytes; may induce DNA cleavage.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Sandeep Khurana et al.
PloS one, 7(2), e32006-e32006 (2012-02-24)
Bile acids (BAs) regulate cardiovascular function via diverse mechanisms. Although in both health and disease serum glycine-conjugated BAs are more abundant than taurine-conjugated BAs, their effects on myogenic tone (MT), a key determinant of systemic vascular resistance (SVR), have not
Yong Zhou et al.
American journal of physiology. Gastrointestinal and liver physiology, 298(5), G722-G731 (2010-03-06)
The injurious effect of nonsteroidal anti-inflammatory drugs (NSAIDs) in the small intestine was not appreciated until the widespread use of capsule endoscopy. Animal studies found that NSAID-induced small intestinal injury depends on the ability of these drugs to be secreted
Lutz Schneider et al.
Pancreas, 38(6), 676-680 (2009-07-25)
Calcitonin gene-related peptide (CGRP) is released from perivascular pancreatic nerves. It effects vasomotion and cytokine liberation in inflammatory processes, including acute pancreatitis (AP). Calcitonin gene-related peptide liberation is stimulated by capsaicin, a substance of red hot chili peppers. Aim of
Jesper Østergaard et al.
Journal of separation science, 32(10), 1712-1721 (2009-05-28)
The practical and theoretical problems associated with interpretation of binding isotherms obtained by the investigation of weak analyte-ligand interactions using mobility shift affinity CE were investigated with special emphasis on various correction methods to compensate for media effects due to
Kai A Bachmann et al.
Critical care (London, England), 17(6), R281-R281 (2013-12-10)
Severe acute pancreatitis is still a potentially life threatening disease with high mortality. The aim of this study was to evaluate the therapeutic effect of thoracic epidural anaesthesia (TEA) on survival, microcirculation, tissue oxygenation and histopathologic damage in an experimental
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