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Merck
CN

G8919

Sigma-Aldrich

Anti-Growth Hormone Receptor antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-GHR

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

mouse

技术

immunohistochemistry: 5-15 μg/mL using cells and tissues
western blot: 0.1-0.2 μg/mL

UniProt登记号

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

mouse ... Ghr(14600)

一般描述

By immunoblotting, this antibody shows ~50% cross-reactivity with recombinant rat GHR and 20% cross-reactivty with recombinant human GHR.
Growth Hormone Receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of intra- and intercellular signal transduction pathways.

免疫原

purified, NSO-derived, recombinant mouse growth hormone receptor extracellular domain.

应用

Anti-Growth Hormone Receptor antibody produced in goat was used to study the protein and protein phosphorylation levels in rat primary hippocampal cultures using Li-cor Odyssey fluorescence technology.

生化/生理作用

Growth hormone (GH) is secreted by the anterior pituitary and functions by binding specific growth hormone receptor (GHR). GH stimulates the secretion of insulin-like growth factor-1 that mediates some of its growth promoting actions. The activity of GH/GHR is important for normal physiology and aging processes.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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