Anti-Fas Antibody

The FAS receptor (FasR) is a protein encoded by the TNFRSF6 gene in humans and is mapped to chromosomal band 10q24.1. It is a cell surface antigen expressed on a variety of normal and malignant cells.

Immunogen Sequence: GI # 4507583, sequence 21-165

Recombinant tumor necrosis factor receptor superfamily, member 6 isoform 1

Anti-FAS (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

The FAS receptor (FasR) is associated with programmed cell death (apoptosis). It functions as an apoptosis-signaling cell surface Ag. Mutation of the gene or defective FAS signaling may render the T-cell lymphoblastic lymphomas (T-LBLs) tumor cells resistant to apoptotic cell death.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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