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H177

2-Hydroxytetradecanoic acid

powder

别名:

2-Hydroxymyristic acid, DL-α-Hydroxymyristic acid

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关于此项目

经验公式（希尔记法）:
C14H28O3
化学文摘社编号:
2507-55-3
分子量:
244.37
EC Number:
219-714-0
UNSPSC Code:
12352200
MDL number:
MFCD00014342
Beilstein/REAXYS Number:
1725369
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form

powder

color

white

solubility

DMSO: 4 mg/mL (with heating in a 70°C water bath), H2O: 5 mg/mL

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCC(O)C(O)=O

InChI

1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)

InChI key

JYZJYKOZGGEXSX-UHFFFAOYSA-N

法规信息

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分析证书(COA)

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A B Vaandrager et al.
The Journal of biological chemistry, 271(12), 7025-7029 (1996-03-22)
The apical membrane of intestinal epithelial cells harbors a unique isozyme of cGMP-dependent protein kinase (cGK type II) which acts as a key regulator of ion transport systems, including the cystic fibrosis transmembrane conductance regulator (CFTR)-chloride channel. To explore the
L A Paige et al.
Biochemistry, 29(46), 10566-10573 (1990-11-20)
The importance of myristoylation for the proper biological functioning of many acylated proteins has generated interest in the enzymes of the myristoylation pathway and their interactions with substrates and inhibitors. Previous observations that S-(2-oxopentadecyl)-CoA, a nonhydrolyzable methylene-bridged analogue of myristoyl-CoA
M J Nadler et al.
Biochemistry, 32(35), 9250-9255 (1993-09-07)
N-Myristoylation of p56lck, a member of the Src family of protein-tyrosine kinases, is essential for its proper targeting to the plasma membrane. 2-Hydroxymyristic acid (HMA) is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA