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H2255

5-Hydroxyindole-3-acetic acid (dicyclohexylammonium) salt

Name: 5-Hydroxyindole-3-acetic acid (dicyclohexylammonium) salt
Brand: SIGMA

crystalline, ≥98% (TLC)

别名:

5-HIAA

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经验公式（希尔记法）:

C₁₀H₉NO₃ · C₁₂H₂₃N

化学文摘社编号:

66866-39-5

分子量:

372.50

UNSPSC Code:

12352200

PubChem Substance ID:

329815184

MDL number:

MFCD00069704

Assay:

≥98% (TLC)

Form:

crystalline

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assay

≥98% (TLC)

form

crystalline

color

white

storage temp.

−20°C

SMILES string

C1CCC(CC1)NC2CCCCC2.OC(=O)Cc3c[nH]c4ccc(O)cc34

InChI

1S/C12H23N.C10H9NO3/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h11-13H,1-10H2;1-2,4-5,11-12H,3H2,(H,13,14)

InChI key

NIDSGTAJKGNSEN-UHFFFAOYSA-N

Biochem/physiol Actions

Major serotonin metabolite.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Season of sampling and season of birth influence serotonin metabolite levels in human cerebrospinal fluid.

Jurjen J Luykx et al.

PloS one, 7(2), e30497-e30497 (2012-02-09)

Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal patterns in CSF MA turnover in a large set of healthy adults. Standardized amounts of CSF were prospectively collected

ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation.

U Knigge et al.

Neuroendocrinology, 105(3), 310-319 (2017-02-22)

Subchronic glucocorticoids, glutathione depletion and a postpartum model elevate monoamine oxidase a activity in the prefrontal cortex of rats.

Sofia Raitsin et al.

Brain research, 1666, 1-10 (2017-04-25)

Recent human brain imaging studies implicate dysregulation of monoamine oxidase-A (MAO-A), in particular in the prefrontal cortex (PFC) and anterior cingulate cortex (ACC), in the development of major depressive disorder (MDD). This study investigates the influence of four alterations underlying

Homeostasis Imbalance of Microglia and Astrocytes Leads to Alteration in the Metabolites of the Kynurenine Pathway in LPS-Induced Depressive-Like Mice.

Xue Tao et al.

International journal of molecular sciences, 21(4) (2020-02-27)

In the pathology-oriented study of depression, inflammation hypothesis has received increasing attention for recent years. To mimic the depressive state caused by inflammation, rodents injected intraperitoneally with lipopolysaccharide (LPS) are usually used to stimulate an immune response. However, the dose

Determination of endogenous substance change in PM2.5-induced rat plasma and lung samples by UPLC-MS/MS method to identify potential markers for lung impairment.

Ronghua Fan et al.

Environmental science and pollution research international, 26(21), 22040-22050 (2019-05-31)

Exposure to fine particulate matter (PM2.5) could induce lung impairment aggravation. Moreover, endogenous substances are known to play a significant role in lung impairment. Therefore, the research objectives was to investigate the influence of PM2.5-induced lung impairment on the levels

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