Product Name
白介素1α 人, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
生物来源
human
质量水平
重组
expressed in E. coli
方案
≥98% (SDS-PAGE and HPLC)
表单
lyophilized powder
质量
endotoxin tested
分子量
~17 kDa
包装
pkg of 2 and 10 μg
技术
cell culture | mammalian: suitable
UniProt登记号
储存温度
−20°C
基因信息
human ... IL1A(3552)
一般描述
Interleukin-1α (IL-1α) is a cytokine that belongs to the interleukin-1 (IL-1) family. It is located intracellularly in hematopoietic and non-hematopoietic cells. IL-1α gene is located on the human chromosome at 2q14.1.
应用
Interleukin-1α (IL-1α) has been used:
- to study its effects on human colorectal adenocarcinoma cells
- to stimulate primary human fetal retinal pigment epithelium (hfRPE) cells
- to pre-stimulate human THP-1 monocytes
生化/生理作用
Interleukin-1α (IL-1α) plays a crucial role in inflammation during cell necrosis. It also regulates the recruitment of interleukin-1β (IL-1β), neutrophils, chemokines, and other cytokines at the site of injury. IL-1α exhibits a dual function of binding to its cell surface receptor as well as chromatin.
外形
Lyophilized from 0.2 μm filtered 10 mM sodium phosphate , pH 8.0, plus 50 mm NaCl and 50 μg bovine serum albumin (BSA) per μg cytokine.
分析说明
The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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