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L5386

[des-Gly10, D-Trp6]-LH-RH ethylamide

≥97% (HPLC)

别名:

Deslorelin

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关于此项目

经验公式（希尔记法）:
C64H83N17O12
化学文摘社编号:
57773-65-6
分子量:
1282.45
UNSPSC Code:
12352200
PubChem Substance ID:
329817623
MDL number:
MFCD00167401
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assay

≥97% (HPLC)

UniProt accession no.

P55248, P01148, P07490, P13562, P30968, P30969, Q01776

storage temp.

−20°C

SMILES string

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](CO)NC(=O)[C@H](Cc5c[nH]c6ccccc56)NC(=O)[C@H](Cc7c[nH]cn7)NC(=O)[C@@H]8CCC(=O)N8

InChI

1S/C64H83N17O12/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69)/t45-,46-,47-,48-,49+,50-,51-,52-,53-/m0/s1

InChI key

GJKXGJCSJWBJEZ-XRSSZCMZSA-N

Gene Information

human ... GNRH1(2796), GNRHR(2798)
mouse ... GNRH1(14714), GNRHR(14715)
rat ... GNRH1(25194), GNRHR(81668)

Biochem/physiol Actions

Long-acting LH-RH agonist.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360

Hazard Classifications

Repr. 1B

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
118H0507
088H0900
088H09001
055H0642
049H1300

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Marta Cecchetto et al.
Journal of feline medicine and surgery, 19(12), 1224-1230 (2017-02-15)
Objectives The purpose of this study was to assess efficacy of deslorelin, a gonadotropin-releasing hormone (GnRH) agonist marketed in Europe for the control of male dog reproduction, for the postponement of puberty in queens. Methods Nine prepubertal queens aged 3-9
Robert M Kirberger et al.
BMC veterinary research, 13(1), 312-312 (2017-11-08)
Cheetahs in captivity have a high prevalence of chronic renal diseases. We ultrasonographically evaluated the renal volumes, a variety of renal dimensions, interarcuate artery resistive indices (RI) as well as aortic diameters and the length of the ventral aspect of the
D Kaya et al.
Reproduction in domestic animals = Zuchthygiene, 52(6), 1104-1112 (2017-10-01)
The goals of this study were as follows: (Experiment 1) to examine the basic capability of canine corpora lutea (CL) to respond to GnRH by assessing expression of gonadotropin-releasing hormone receptor (GnRH-R) in luteal samples collected throughout the luteal lifespan
Wojciech Niżański et al.
Animals : an open access journal from MDPI, 10(12) (2020-12-17)
This article presents B-mode and color Doppler imaging of the prostate and testes in dogs suffering from benign prostate hyperplasia (BPH), and receiving deslorelin acetate (SuprelorinTM) or osaterone acetate (YpozaneTM). The study was planned as a controlled clinical trial, dogs
S A Colgan et al.
Australian veterinary journal, 97(12), 515-523 (2019-11-21)
A large-scale capture method was developed to enable sterilisation of a macropod population in western Sydney from 2005 to 2018. Until March 2007, free ranging eastern grey kangaroos and red kangaroos were herded into purpose-built 15 m diameter capture yards
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