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Merck
CN

M6502

6-Methylpurine

≥99%

别名:

MeP

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关于此项目

经验公式（希尔记法）:
C6H6N4
化学文摘社编号:
2004-03-7
分子量:
134.14
NACRES:
NA.51
PubChem Substance ID:
24897013
UNSPSC Code:
41106305
EC Number:
217-903-2
MDL number:
MFCD00083663
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
Storage temp.:
−20°C

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biological source

synthetic (organic)

Quality Level

100

assay

≥99%

form

powder

mp

237-238 °C (lit.)

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cc1ncnc2[nH]cnc12

InChI

1S/C6H6N4/c1-4-5-6(9-2-7-4)10-3-8-5/h2-3H,1H3,(H,7,8,9,10)

InChI key

SYMHUEFSSMBHJA-UHFFFAOYSA-N

Application

6-Methylpurine (MeP) is a toxic adenine analog used as a bisubstrate inhibitor of enzymes that bind adenosyl moieties and which may become phosphorylated to levels that inhibit RNA and protein synthesis.

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCT9866
MKCT1027
MKCS7810
MKCT4073
MKCR6257

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H Ohgaki et al.
Journal of cancer research and clinical oncology, 117(1), 13-18 (1991-01-01)
The formation of O6-methyldeoxyguanosine (O6-MedGuo) was determined by an immuno-slot-blot assay in DNA of various tissues of F344 rats exposed to N-methyl-N-nitrosourea (MNU) in the drinking water at 400 ppm for 2 weeks. Although the pyloric region of the glandular
G Klobus et al.
Plant physiology, 87, 878-882 (1988-01-01)
The nature of the injury and recovery of nitrate uptake (net uptake) from NaCl stress in young barley (Hordeum vulgare L, var CM 72) seedlings was investigated. Nitrate uptake was inhibited rapidly by NaCl, within 1 minute after exposure to
Manuel Ellermann et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(23), 6369-6381 (2011-05-04)
L-Dopa, the standard therapeutic for Parkinson's disease, is inactivated by the enzyme catechol-O-methyltransferase (COMT). COMT catalyzes the transfer of an activated methyl group from S-adenosylmethionine (SAM) to its catechol substrates, such as L-dopa, in the presence of magnesium ions. The
T Nobori et al.
Biochemical and biophysical research communications, 137(3), 998-1005 (1986-06-30)
Patients with 2,8-dihydroxyadenine urolithiasis are either completely or partially deficient in adenine phosphoribosyltransferase activities. Patients with partial enzyme deficiencies, all of whom have been found among Japanese, are homozygotes having a unique mutant adenine phosphoribosyltransferase gene (APRT*J) in double dose
Theodoros Potouridis et al.
BMC chemistry, 13(1), 70-70 (2019-08-07)
Parabens and sorbic acid are commonly used as food preservatives due to their antimicrobial effect. However, their use in foods for infants and young children is not permitted in the European Union. Previous studies found these compounds in some gel-filled
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全球贸易项目编号

货号GTIN
M6502-250MG04061831584028
M6502-100MG04061831584011

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