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Merck
CN

M7031

13-Methylmyristic acid

≥98% (capillary GC)

别名:

13-Methyltetradecanoic acid

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关于此项目

经验公式(希尔记法):
C15H30O2
化学文摘社编号:
分子量:
242.40
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
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assay

≥98% (capillary GC)

form

solid

functional group

carboxylic acid

shipped in

ambient

storage temp.

2-8°C

SMILES string

CC(C)CCCCCCCCCCCC(O)=O

InChI

1S/C15H30O2/c1-14(2)12-10-8-6-4-3-5-7-9-11-13-15(16)17/h14H,3-13H2,1-2H3,(H,16,17)

InChI key

ZOCYQVNGROEVLU-UHFFFAOYSA-N

Biochem/physiol Actions

13-Methyltetradecanoic acid (13-Methylmyristic acid, 13-MTD, 13-MTDA), an iso-fatty acid, is used to study the induction of mitochondrial-mediated apoptosis via the AKT and MAPK pathways. 13-MTDA is used for the biosynthesis of methyl-branched polyhydroxyalkanoates.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

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Sawitree Wongtangtintharn et al.
Journal of nutritional science and vitaminology, 50(2), 137-143 (2004-07-10)
This paper describes the antitumoral activity of branched-chain fatty acid (BCFA) in human breast cancer cells with an emphasis on its effect on fatty acid biosynthesis. First, the relationship between chain-length and antitumoral activity was studied. The highest activity was
Tianxin Lin et al.
Urologic oncology, 30(3), 339-345 (2010-09-17)
13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid purified from soy fermentation products, is known to induce apoptosis in many types of human cancer cells. This study was designed to investigate the molecular mechanisms involved in 13-MTD-induced apoptosis in human
Michael W Ring et al.
The Journal of biological chemistry, 281(48), 36691-36700 (2006-09-23)
Iso-fatty acids (FAs) are the dominant FA family in all myxobacteria analyzed. Furthermore, it was postulated that iso-FAs or compounds derived thereof are involved in fruiting body formation in Myxococcus xanthus, since mutants with a reduced level of iso-FA due
Sawitree Wongtangtintharn et al.
Lipids in health and disease, 4, 29-29 (2005-11-25)
13-Methyltetradecanoic acid (13-MTD), an iso-C15 branched- chain saturated fatty acid, has been shown to induce apoptotic cell death of numerous human cancer cells. However, the mechanism for the induction of apoptosis has not been fully understood. This study described the
N Kadri-Hassani et al.
The Journal of biological chemistry, 270(25), 15111-15118 (1995-06-23)
We studied the translocation of protein kinase C (PKC), the endogenous phosphorylation and presence in the membrane fraction of p47phox (the 47-kDa cytosolic component of the phagocyte NADPH oxidase), and the O-.2 production in human adherent monocytes (HAMs). This was

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