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M9024

MOPS 钠盐

BioPerformance Certified, suitable for cell culture, ≥99.5%

别名:

3-(N-吗啉基)丙磺酸 钠盐, 4-吗啉丙磺酸 钠盐

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关于此项目

经验公式（希尔记法）:
C7H14NNaO4S
化学文摘社编号:
71119-22-7
分子量:
231.25
NACRES:
NA.25
PubChem Substance ID:
24897311
UNSPSC Code:
12161700
MDL number:
MFCD00064350
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grade

BioPerformance Certified

Quality Level

400

assay

≥99.5%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and bioburden, tested

useful pH range

6.5-7.9

pKa (25 °C)

7.2

anion traces

≤0.0005% (Lead (Pb))

suitability

suitable for determination of protein concentration

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, NICKase and protease, none detected

SMILES string

[Na+].[O-]S(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8;/h1-7H2,(H,9,10,11);/q;+1/p-1

InChI key

MWEMXEWFLIDTSJ-UHFFFAOYSA-M

General description

MOPS is a morpholino propanesulfonic acid sodium salt, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.), developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK a with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized.

Application


  • 缓冲剂不仅仅是缓冲剂：为蛋白质BSA引入一类新的稳定剂。：该研究强调了MOPS钠盐作为牛血清白蛋白（BSA）新型稳定剂的用途，使其作用超越了简单的缓冲剂。该研究展示了MOPS钠盐如何在各种条件下提高BSA的稳定性，为生化应用和生物化学研究提供了重要启示（Gupta BS et al., 2015）。


Features and Benefits

Features:
  1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
  2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
  3. M-Clarity™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity™ Program
  4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
  5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
  6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
    1. Site quality assessment
    2. ISO 9001 certificate
    3. Detailed product specifications
    4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
Benefits:
  1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
  2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
  3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
  4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
  5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
  6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Other Notes

使用 MOPS 钠盐规格表可以非常轻松比较 MOPS 钠盐产品规格。

Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany

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存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000541168
0000535243
0000535244
0000535245
0000539377

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Biotechnology progress, 31(4), 974-982 (2015-05-29)
Protein A chromatography is widely employed for the capture and purification of monoclonal antibodies (mAbs). Because of the high cost of protein A resins, there is a significant economic driving force to seek new downstream processing strategies. Membrane chromatography has

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