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N138

(+)-去甲美他佐辛

Name: (+)-去甲美他佐辛
Brand: SIGMA

别名:

(+)-(2S,[2α,6α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇

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关于此项目

经验公式（希尔记法）:

C₁₄H₁₉NO

化学文摘社编号:

16670-83-0

分子量:

217.31

UNSPSC Code:

41116107

PubChem Substance ID:

329818573

MDL number:

MFCD00167442

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属性

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

SMILES string

C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2

InChI

1S/C14H19NO/c1-9-13-7-10-3-4-11(16)8-12(10)14(9,2)5-6-15-13/h3-4,8-9,13,15-16H,5-7H2,1-2H3/t9-,13+,14+/m1/s1

InChI key

DXESFJJJWBHLJX-IIMNLJJBSA-N

说明

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (sigma 1) site and quantitative structure-affinity relationship studies.

S W Mascarella et al.

Journal of medicinal chemistry, 38(3), 565-569 (1995-02-03)

sigma 1 receptor ligands have potential pharmacological significance as antipsychotic drugs, as tools in the study of drug-induced motor function disorders, and as radiopharmaceutical imaging agents for the noninvasive imaging of malignant tumors in human subjects. A series of substituted

Agonist-antagonist actions and stereoselectivity of optical pairs of some N-substituted alpha-N-normetazocines.

M D Aceto et al.

Journal of pharmaceutical sciences, 73(12), 1864-1866 (1984-12-01)

alpha-(-)-, (+)-, and (+/-)-N-4-Methylpentyl-, (-)- and (+)-N-cis-3-chloroallyl-, and (-)- and (+)-N-propynyl-N-normetazocine (I, II, and III, respectively) have been prepared from alpha-(-)-, (+)-, and (+/-)-N-normetazocine (IV) and tested for antinociceptive activity in mice and in morphine-dependent rhesus monkeys. The results obtained

Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues.

R Danso-Danquah et al.

Journal of medicinal chemistry, 38(15), 2986-2989 (1995-07-21)

The synthesis and sigma 1 and sigma 2 binding properties of several 1'- and 3'-halo- and 1',3'-dihalo-substituted analogues of (+)-N-benzyl- and (+)- and (-)-N-dimethylallyl-N-normetazocine are presented. Structure-activity relationship analyses of the binding data showed that halogen substitution at the 1'-position

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货号	GTIN
MABN40	04053252479045