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Merck
CN

N8285

β-烟酰胺腺嘌呤二核苷酸

greener alternative

pkg of 10 mg (per vial)

别名:

β-DPN, β-NAD, DPN, 二磷酸吡啶核苷酸, 氧化型辅酶 I, 辅酶, 辅酶 1

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关于此项目

经验公式（希尔记法）:
C21H27N7O14P2
化学文摘社编号:
53-84-9
分子量:
663.43
NACRES:
NA.51
PubChem Substance ID:
57654466
eCl@ss:
39200202
UNSPSC Code:
41106305
EC Number:
200-184-4
MDL number:
MFCD00036253
Beilstein/REAXYS Number:
3584133
Form:
powder
Solubility:
H2O: soluble-50 mg/mL, clear, colorless
Biological source:
yeast

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Quality Level

200

biological source

yeast

form

powder

packaging

pkg of 10 mg (per vial)

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

solubility

H2O: soluble-50 mg/mL, clear, colorless

greener alternative category

DfS-Developed

storage temp.

−20°C

SMILES string

NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Gene Information

human ... ESR1(2099), ESR2(2100)

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相关类别

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application

β-烟酰胺腺嘌呤二核苷酸（β-NAD）用于制备脱乙酰基微管蛋白。也用于口腔成纤维细胞裂解物 UDP-葡萄糖-6-氢化酶（UGDH）的酶活性测定。

Biochem/physiol Actions

β-烟酰胺腺嘌呤二核苷酸（β-NAD）是神经调节剂和抑制性神经递质，是嘌呤能（P2Y1）受体的激动剂。
β-烟酰胺腺嘌呤二核苷酸（NAD+）和 β-还原型烟酰胺腺嘌呤二核苷酸（NADH）包含辅酶氧化还原对（NAD + NADH），参与一系列酶催化氧化还原反应。 除了其氧化还原功能外，NAD +/NADH 是 ADP-核糖基转移酶（ADP-核糖基转移酶；聚（ADP-核糖）聚合酶）反应中的 ADP-核糖单元的供体，也是环状ADP-核糖（ADP-核糖基环化酶）的前体。
电子受体

Other Notes

本品是普通型 NAD。
根据由紫外可见分光光度计测定的 NAD 含量包装。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000526996
0000526996
0000475855
0000475855
0000417252

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PLoS ONE, 7(10), e48204-e48204 (2012)
Violeta N Mutafova-Yambolieva et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(41), 16359-16364 (2007-10-05)
Peripheral inhibitory nerves are physiological regulators of the contractile behavior of visceral smooth muscles. One of the transmitters responsible for inhibitory neurotransmission has been reputed to be a purine, possibly ATP. However, the exact identity of this substance has never
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UDP-glucose dehydrogenase (UGDH) catalyzes the formation of UDP-glucuronate. Glucuronate represents an integral component of the glycosaminoglycan, hyaluronan, which accumulates in orbital Graves disease. Here we report that orbital fibroblasts express higher levels of UGDH than do those from skin. This
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Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
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全球贸易项目编号

货号GTIN
N8285-15VL04061834118503

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