P0880
Pro-Gly
≥98% (TLC), suitable for cell culture
别名:
L-prolyl-glycine
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关于此项目
经验公式（希尔记法）:
C7H12N2O3
化学文摘社编号:
分子量:
172.18
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
Pro-Gly,
SMILES string
OC(=O)CNC(=O)[C@@H]1CCCN1
InChI
1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1
InChI key
RNKSNIBMTUYWSH-YFKPBYRVSA-N
assay
≥98% (TLC)
form
powder
technique(s)
cell culture | mammalian: suitable
color
white
application(s)
cell analysis
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
PRO-GLY is a dipeptide that has previously been shown to prevent progression of diabetes.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
T A Gudasheva et al.
European journal of drug metabolism and pharmacokinetics, 22(3), 245-252 (1997-07-01)
The metabolism of a new piracetam analogue, the dipeptide cognitive enhancer N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111) was studied in vivo. GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection (LOD)
Daisuke Motooka et al.
Biopolymers, 98(2), 111-121 (2011-10-25)
Extensive studies on the structure of collagen have revealed that the hydroxylation of Pro residues in a variety of model peptides with the typical (X-Y-Gly)(n) repeats (X and Y: Pro and its analogues) represents one of the major factors influencing
[Effects of dipeptides Gly-Pro, Pro-Gly, glycine, and proline on the cardiotropic effect of acetylcholine].
N E Babskaia et al.
Biulleten' eksperimental'noi biologii i meditsiny, 126(8), 139-141 (1998-10-20)
Yasutaka Shigemura et al.
Journal of agricultural and food chemistry, 60(20), 5128-5133 (2012-05-03)
Elastin hydrolysate has apparent beneficial effects, and the food-derived peptide prolyl-glycine (Pro-Gly) is present in human blood after oral ingestion. Following ingestion of elastin hydrolysate (10 g/60 kg body weight) by healthy human volunteers, peripheral blood was used to prepare
Z Dzakula et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 135(2), 454-465 (1999-01-08)
Analytical expressions have been derived that translate uncertainties in distance constraints (obtained from NMR investigations) into uncertainties in atom positions in the maximum likelihood (ML) structure consistent with these inputs. As a test of this approach, a comparison was made
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