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Merck
CN

R7882

视黄醇乙酸酯

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

别名:

维生素 A 醋酸酯, 醋酸维生素 A

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关于此项目

经验公式(希尔记法):
C22H32O2
化学文摘社编号:
分子量:
328.49
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
34058009
UNSPSC Code:
12352205
EC Number:
204-844-2
MDL number:
Beilstein/REAXYS Number:
1915439
Assay:
≥90% (HPLC)
Form:
solid or viscous liquid
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InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

biological source

synthetic

product line

BioReagent

assay

≥90% (HPLC)

form

solid or viscous liquid

potency

~2,800,000 I.U. per g

mol wt

Mw 328.49 g/mol

technique(s)

cell culture | mammalian: suitable

color

light yellow to dark yellow

mp

57-58 °C

solubility

absolute ethanol: 25 mg/mL (lit.)

storage temp.

−20°C

Quality Level

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General description

视黄醇乙酸酯是维生素A的天然酯衍生物。 它可用于M-199、NCTC-109和William′培养基等经典培养基。维生素A是血清的一种成分,可用于大多数具有一定维生素A水平的含血清细胞培养系统。

Application

视黄醇乙酸酯已被用作高效液相色谱分析(HPLC)中测量维生素C浓度的标准品,并可用作制备完整培养基的补充剂。

Biochem/physiol Actions

视黄酸是视黄醇的氧化形式,其对于上皮细胞和相关细胞类型(尤其是神经细胞)具有激素样生长因子和分化活性。视黄酸可诱导胚胎干细胞成为神经细胞。现已确知视黄醇乙酸酯可有效治疗乳腺癌。

Preparation Note

这种材料的熔点约为58°C。为了便于包装,其已被熔化并以结晶固体或过冷粘稠液体的形式存在。

Other Notes

全反式

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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