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关于此项目
NACRES:
NA.84
UNSPSC Code:
41116158
Gene information:
human ... CCL22(6367)
Input:
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
sample type urine
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/mL
standard curve range: 1.65-400 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CCL22(6367)
General description
Human MDC / CCL22 enzyme-linked immunosorbent assay (ELISA) kit is an in vitro assay for the quantitative measurement of macrophage-derived chemokine (MDC) protein in biological samples, such as serum, plasma, cell culture supernatants, urine, and/or cell and tissue lysates.
Immunogen
Recombinant Human MDC
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Macrophage-derived chemokine (MDC) signals through the C-C chemokine receptor type 4 (CCR4). It chemo-attracts monocytes, dendritic cells and natural killer (NK) cells and aids in their function. The protein exerts human immunodeficiency virus (HIV) suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. It is expressed in various cancers and is involved in recruitment of regulatory T cells (Treg) within a tumor.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Genetic Polymorphisms of CCL22 and CCR4 in Patients with Lung Cancer.
Erfani N
Iranian Journal of Medical Sciences (2014)
Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.
Godiska R
The Journal of Experimental Medicine (1997)
Suppression of intratumoral CCL22 by type i interferon inhibits migration of regulatory T cells and blocks cancer progression.
Anz D
Cancer Research (2015)
Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of ? chemokines and RNases.
Cocchi F
Proceedings of the National Academy of Sciences of the USA (2012)
Yang Zhang et al.
Bioscience, biotechnology, and biochemistry, 84(6), 1191-1200 (2020-03-07)
The molecular mechanism of autophagy in Lactoferrin (LF) induced osteoblast differentiation is not fully demonstrated. In this study, alkaline phosphatase (ALP) activity, alizarin red S staining and ELISA were used to study N-terminal propeptide of type I procollagen (PINP) expression.
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