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NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Ccl27(20301)
Input:
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 24.69-18000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ccl27(20301)
General description
The Mouse CTACK ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse CTACK in serum, plasma, cell culture supernatants and urine.
The CCL27 (C-C motif chemokine ligand 27) gene codes for a T cell skin-homing chemokine and is expressed in epidermal keratinocytes. It is also referred to as cutaneous T cell-attracting chemokine (CTACK).
The CCL27 (C-C motif chemokine ligand 27) gene codes for a T cell skin-homing chemokine and is expressed in epidermal keratinocytes. It is also referred to as cutaneous T cell-attracting chemokine (CTACK).
Immunogen
Recombinant Mouse CTACK
Application
请参考Protocol了解详情。
Biochem/physiol Actions
CCL27 (C-C motif chemokine ligand 27) contributes to the progression of inflammatory skin diseases. In animal models, atopic dermatitis is known to increase the CCL27 gene expression. The CCL27 gene is downregulated in cancer. It regulates the enrollment of T cells to inflamed skin.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model.
Chen L, et al.
International Immunology, 18(8), 1233-1242 (2006)
Tumor immune escape by the loss of homeostatic chemokine expression.
Pivarcsi A, et al.
Proceedings of the National Academy of Sciences of the USA, 104(48), 19055-19060 (2007)
CCL27?transgenic mice show enhanced contact hypers ensitivity to Th2, but not Th1 stimuli.
Kagami S, et al.
European Journal of Immunology, 38(3), 647-657 (2008)
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